Gene Symbol |
COMMD2
|
Entrez Gene |
51122
|
Alt Symbol |
HSPC042
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
COMM domain containing 2
|
Other Description |
COMM domain-containing protein 2
|
Swissprots |
Q9H3L5 Q561V4 Q86X83 Q9Y5V1
|
Accessions |
EAW78866 EAW78867 Q86X83 AF059618 AAG43117 AF125096 AAD39913 AK055223 AY542158 AAS22240 BC001228 BC022206 BC046131 AAH46131 BC093077 AAH93077 BG700015 BI792102 BM981499 BQ216242 BU633168 DA811158 HQ448624 ADQ33102 XM_011512874 XP_011511176 XR_924145 NM_016094 NP_057178
|
Function |
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:21778237}.
|
Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:15799966}.
|