Gene Symbol | COMMD2 |
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Entrez Gene | 51122 |
Alt Symbol | HSPC042 |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 2 |
Other Description | COMM domain-containing protein 2 |
Swissprots | Q9H3L5 Q561V4 Q86X83 Q9Y5V1 |
Accessions | EAW78866 EAW78867 Q86X83 AF059618 AAG43117 AF125096 AAD39913 AK055223 AY542158 AAS22240 BC001228 BC022206 BC046131 AAH46131 BC093077 AAH93077 BG700015 BI792102 BM981499 BQ216242 BU633168 DA811158 HQ448624 ADQ33102 XM_011512874 XP_011511176 XR_924145 NM_016094 NP_057178 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21778237}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15799966}. |
COMMD2 CRISPR/Cas9 KO Plasmid (h) - sc-412120 from Santa Cruz Biotechnology
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COMMD2 HDR Plasmid (h) - sc-412120-HDR from Santa Cruz Biotechnology
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COMMD2 Double Nickase Plasmid (h) - sc-412120-NIC from Santa Cruz Biotechnology
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COMMD2 Double Nickase Plasmid (h2) - sc-412120-NIC-2 from Santa Cruz Biotechnology
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COMMD2 CRISPR Activation Plasmid (h) - sc-412120-ACT from Santa Cruz Biotechnology
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COMMD2 CRISPR Activation Plasmid (h2) - sc-412120-ACT-2 from Santa Cruz Biotechnology
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COMMD2 Lentiviral Activation Particles (h) - sc-412120-LAC from Santa Cruz Biotechnology
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COMMD2 Lentiviral Activation Particles (h2) - sc-412120-LAC-2 from Santa Cruz Biotechnology
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COMMD2 siRNA (h) - sc-78332 from Santa Cruz Biotechnology
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COMMD2 shRNA Plasmid (h) - sc-78332-SH from Santa Cruz Biotechnology
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COMMD2 shRNA (h) Lentiviral Particles - sc-78332-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6415 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6415 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06996 from Sigma-Aldrich
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COMMD2 siRNA (Human) - CRH9541 from Cohesion Biosciences
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COMMD2 - MBS8239462 from MyBioSource
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shRNA set against Human COMMD2 (NM_016094.3) - SHH267581 from Creative biogene
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COMMD2 shRNA Plasmid (Human) - CHH9541 from Cohesion Biosciences
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COMMD2 miRNA 3'UTR clone - MiUTR3H-14491 from Creative biogene
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