Gene Symbol | COMMD2 |
---|---|
Entrez Gene | 51122 |
Alt Symbol | HSPC042 |
Species | Human |
Gene Type | protein-coding |
Description | COMM domain containing 2 |
Other Description | COMM domain-containing protein 2 |
Swissprots | Q9H3L5 Q561V4 Q86X83 Q9Y5V1 |
Accessions | EAW78866 EAW78867 Q86X83 AF059618 AAG43117 AF125096 AAD39913 AK055223 AY542158 AAS22240 BC001228 BC022206 BC046131 AAH46131 BC093077 AAH93077 BG700015 BI792102 BM981499 BQ216242 BU633168 DA811158 HQ448624 ADQ33102 XM_011512874 XP_011511176 XR_924145 NM_016094 NP_057178 |
Function | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21778237}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15799966}. |