SH2B3

Gene Symbol SH2B3
Entrez Gene 10019
Alt Symbol IDDM20, LNK
Species Human
Gene Type protein-coding
Description SH2B adaptor protein 3
Other Description SH2B adapter protein 3|lymphocyte-specific adapter protein Lnk|signal transduction protein Lnk
Swissprots Q9UQQ2 O95184 B9EGG5
Accessions CBX47467 EAW97955 EAW97956 Q9UQQ2 AB208911 BAD92148 AF055581 AAC71695 AJ012793 CAB42642 AK025666 AK025745 AK302173 BAH13642 BC015786 AAH15786 BC136451 AAI36452 XM_005253818 XP_005253875 XM_005253819 XP_005253876 XM_006719180 XP_006719243 XM_011537719 XP_011536021 XM_011537720 XP_011536022 XM_011537721 XP_011536023 XM_011537722 XP_011536024 NM_001291424 NP_001278353 NM_005475 NP_005466
Function Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. {ECO:0000250}.
Tissue Specificity Preferentially expressed by lymphoid cell lines.
Top Pathways Neurotrophin signaling pathway

Lnk (A-12) - sc-393709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Lnk (A-12): sc-393709. Western blot analysis of Lnk expression in Jurkat (A), Ramos (B), MOLT-4 (C) and WEHI-231 (D) whole cell lysates.

Lnk (F-9) - sc-514025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Lnk (F-9): sc-514025. Western blot analysis of Lnk expression in non-transfected: sc-117752 (A) and mouse Lnk transfected: sc-121364 (B) 293T whole cell lysates.

Lnk (H-129) - sc-367128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Lnk (H-129): sc-367128. Western blot analysis of Lnk expression in MOLT-4 (A) and Hep G2 (B) whole cell lysates.

Lnk (M-20) - sc-7222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Lnk (M-20): sc-7222. Western blot analysis of Lnk expression in WEHI-231 whole cell lysate.

Lnk (C-20) - sc-19743 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Lnk (C-20): sc-19743. Western blot analysis of Lnk expression in non-transfected: sc-117752 (A) and mouse Lnk transfected: sc-121364 (B) 293T whole cell lysates.

Lnk (N-20) - sc-19741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-LNK antibody - ab128222 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LNK antibody - ab191904 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LNK antibody - ab21203 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-LNK antibody (ab21203) at 0.3 µg/ml + MOLT4 lysate (35µg protein in RIPA buffer). developed using the ECL technique

Anti-LNK antibody [2D8] - ab123890 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D8
All lanes : Anti-LNK antibody [2D8] (ab123890) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY LNK cDNALysates/proteins at 5 µg per lane.

Anti-LNK antibody [6F11] - ab119251 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6F11
All lanes : Anti-LNK antibody [6F11] (ab119251) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNA.Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY LNK cDNA.Lysates/proteins at 5 µg per lane.

Anti-LNK antibody [EPR7342] - ab154848 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7342
All lanes : Anti-LNK antibody [EPR7342] (ab154848) at 1/1000 dilutionLane 1 : Ramos cell lysateLane 2 : MOLT4 cell lysateLane 3 : Raji cell lysateLysates/proteins at 10 µg per lane.

Anti-SH2B3 / LNK Antibody (aa2-11) - LS-C55071 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of MOLT4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SH2B3 / LNK Antibody (clone 2B11) - LS-C337331 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B11
Anti-SH2B3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2B3.

Anti-SH2B3 / LNK Antibody (clone 1E6) - LS-C172892 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E6
Anti-SH2B3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2B3.

Anti-SH2B3 / LNK Antibody (clone 6F11) - LS-C172884 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6F11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SH2B3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SH2B3.

Anti-SH2B3 / LNK Antibody (clone 1F6) - LS-C173048 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F6
Anti-SH2B3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2B3.

Anti-SH2B3 / LNK Antibody (clone 2D8) - LS-C337330 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D8
IHC of paraffin-embedded Human pancreas tissue using anti-SH2B3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-SH2B3 / LNK Antibody (clone 2C9) - LS-C172968 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C9
Anti-SH2B3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2B3.

Anti-SH2B3 / LNK Antibody (C-Terminus) - LS-C153544 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH2B3 / LNK Antibody (aa335-561, Biotin) - LS-C297652 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH2B3 / LNK Antibody (aa335-561, FITC) - LS-C304871 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH2B3 / LNK Antibody - LS-C341041 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH2B3 / LNK Antibody (aa335-561) - LS-C295209 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SH2B3 / LNK.

LNK/SH2B3 Antibody (2D8) - NBP2-00641 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2D8
Western Blot: LNK Antibody (2D8) [NBP2-00641] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LNK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LNK.
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