Gene Symbol | SH2B3 |
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Entrez Gene | 10019 |
Alt Symbol | IDDM20, LNK |
Species | Human |
Gene Type | protein-coding |
Description | SH2B adaptor protein 3 |
Other Description | SH2B adapter protein 3|lymphocyte-specific adapter protein Lnk|signal transduction protein Lnk |
Swissprots | Q9UQQ2 O95184 B9EGG5 |
Accessions | CBX47467 EAW97955 EAW97956 Q9UQQ2 AB208911 BAD92148 AF055581 AAC71695 AJ012793 CAB42642 AK025666 AK025745 AK302173 BAH13642 BC015786 AAH15786 BC136451 AAI36452 XM_005253818 XP_005253875 XM_005253819 XP_005253876 XM_006719180 XP_006719243 XM_011537719 XP_011536021 XM_011537720 XP_011536022 XM_011537721 XP_011536023 XM_011537722 XP_011536024 NM_001291424 NP_001278353 NM_005475 NP_005466 |
Function | Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. {ECO:0000250}. |
Tissue Specificity | Preferentially expressed by lymphoid cell lines. |
Top Pathways | Neurotrophin signaling pathway |
Lnk CRISPR/Cas9 KO Plasmid (h) - sc-404846 from Santa Cruz Biotechnology
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Lnk HDR Plasmid (h) - sc-404846-HDR from Santa Cruz Biotechnology
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Lnk Double Nickase Plasmid (h) - sc-404846-NIC from Santa Cruz Biotechnology
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Lnk Double Nickase Plasmid (h2) - sc-404846-NIC-2 from Santa Cruz Biotechnology
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Lnk CRISPR Activation Plasmid (h) - sc-404846-ACT from Santa Cruz Biotechnology
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Lnk CRISPR Activation Plasmid (h2) - sc-404846-ACT-2 from Santa Cruz Biotechnology
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Lnk Lentiviral Activation Particles (h) - sc-404846-LAC from Santa Cruz Biotechnology
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Lnk Lentiviral Activation Particles (h2) - sc-404846-LAC-2 from Santa Cruz Biotechnology
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Lnk siRNA (h) - sc-40330 from Santa Cruz Biotechnology
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Lnk shRNA Plasmid (h) - sc-40330-SH from Santa Cruz Biotechnology
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Lnk shRNA (h) Lentiviral Particles - sc-40330-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU053031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19246 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19246 from Sigma-Aldrich
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SH2B3 siRNA (Human) - CRH6746 from Cohesion Biosciences
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SH2B3 - MBS8203193 from MyBioSource
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shRNA set against Human Sh2b3 (NM_005475.2) - SHH406482 from Creative biogene
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SH2B3 shRNA Plasmid (Human) - CHH6746 from Cohesion Biosciences
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SH2B3 miRNA 3'UTR clone - MiUTR4H-TG08018 from Creative biogene
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