| Gene Symbol |
SH2B3
|
| Entrez Gene |
10019
|
| Alt Symbol |
IDDM20, LNK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SH2B adaptor protein 3
|
| Other Description |
SH2B adapter protein 3|lymphocyte-specific adapter protein Lnk|signal transduction protein Lnk
|
| Swissprots |
Q9UQQ2 O95184 B9EGG5
|
| Accessions |
CBX47467 EAW97955 EAW97956 Q9UQQ2 AB208911 BAD92148 AF055581 AAC71695 AJ012793 CAB42642 AK025666 AK025745 AK302173 BAH13642 BC015786 AAH15786 BC136451 AAI36452 XM_005253818 XP_005253875 XM_005253819 XP_005253876 XM_006719180 XP_006719243 XM_011537719 XP_011536021 XM_011537720 XP_011536022 XM_011537721 XP_011536023 XM_011537722 XP_011536024 NM_001291424 NP_001278353 NM_005475 NP_005466
|
| Function |
Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. {ECO:0000250}.
|
| Tissue Specificity |
Preferentially expressed by lymphoid cell lines.
|
| Top Pathways |
Neurotrophin signaling pathway
|
![Western Blot: LNK Overexpression Lysate (Adult Normal) [NBL1-15917] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LNK.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4725_LNK%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15917-img0002.jpg)