Gene Symbol | TPPP |
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Entrez Gene | 11076 |
Alt Symbol | TPPP/p25, TPPP1, p24, p25, p25alpha |
Species | Human |
Gene Type | protein-coding |
Description | tubulin polymerization promoting protein |
Other Description | 25 kDa brain-specific protein|brain specific protein p25 alpha|glycogen synthase kinase 3 (GSK3) inhibitor p24|p25-alpha|tubulin polymerization-promoting protein |
Swissprots | O94811 |
Accessions | EAW51015 EAW51016 O94811 AB017016 BAA36164 AI796918 AK054920 BAG51443 AK098392 AW955330 AY319261 AAQ96657 BC040496 AAH40496 BC131506 AAI31507 BC152382 AAI52383 BQ066916 BT020035 AAV38838 BU726600 DB478250 DB546894 XM_005248237 XP_005248294 NM_007030 NP_008961 |
Function | May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. {ECO:0000269|PubMed:17105200, ECO:0000269|PubMed:17693641, ECO:0000269|PubMed:18028908}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10083737}. |
Human Tubulin Polymerization Promoting Protein full length protein - ab167958 from Abcam
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Human Tubulin Polymerization Promoting Protein full length protein - ab161283 from Abcam
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TPPP Antibody Blocking Peptide - LS-E4711 from LifeSpan Bioscience
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TPPP Antibody Blocking Peptide - LS-E22483 from LifeSpan Bioscience
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TPPP Antibody Blocking Peptide - LS-E27260 from LifeSpan Bioscience
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TPPP Antibody Blocking Peptide - LS-E13483 from LifeSpan Bioscience
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TPPP Antibody Blocking Peptide - LS-E13484 from LifeSpan Bioscience
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Recombinant Human TPPP/p25 Protein - H00011076-P01 from Novus Biologicals
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TPPP-Antibody-Center-Blocking-Peptide - BP17081c from Abgent, a WuXi AppTec company
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TPPP blocking peptide - GTX88044-PEP from GeneTex
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Human TPPP protein - orb191263 from Biorbyt
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TPPP Blocking Peptide - 33R-4660 from Fitzgerald
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Human TPPP Protein - abx069525 from Abbexa
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Tubulin Polymerization Promoting Protein Peptide - AC21-2080-P from Abcore
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TPPP - H00011076-P01 from Acris Antibodies
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TPPP - H00011076-Q01-10 from Acris Antibodies
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TPPP Peptide - 42-789P from ProSci
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TPPP fusion protein - Ag19046 from Proteintech Group
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TPPP fusion protein - Ag19159 from Proteintech Group
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Recombinant Human TPPP, His-tagged - TPPP-3373H from Creative Biomart
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Recombinant Tubulin Polymerization Promoting Protein (TPPP) - RPA993Hu01 from Uscn Life Science Inc.
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Recombinant Tubulin Polymerization Promoting Protein (TPPP) - RPA993Mu01 from Uscn Life Science Inc.
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Recombinant Tubulin Polymerization Promoting Protein (TPPP) - RPA993Mu02 from Uscn Life Science Inc.
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Recombinant Tubulin Polymerization Promoting Protein (TPPP) - RPA993Hu01 from Cloud-clone
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Recombinant Human Tubulin polymerization-promoting protein(TPPP) - CSB-YP024115HU CSB-EP024115HU CSB-BP024115HU CSB-MP024115HU from Cusabio
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