TPPP

Gene Symbol TPPP
Entrez Gene 11076
Alt Symbol TPPP/p25, TPPP1, p24, p25, p25alpha
Species Human
Gene Type protein-coding
Description tubulin polymerization promoting protein
Other Description 25 kDa brain-specific protein|brain specific protein p25 alpha|glycogen synthase kinase 3 (GSK3) inhibitor p24|p25-alpha|tubulin polymerization-promoting protein
Swissprots O94811
Accessions EAW51015 EAW51016 O94811 AB017016 BAA36164 AI796918 AK054920 BAG51443 AK098392 AW955330 AY319261 AAQ96657 BC040496 AAH40496 BC131506 AAI31507 BC152382 AAI52383 BQ066916 BT020035 AAV38838 BU726600 DB478250 DB546894 XM_005248237 XP_005248294 NM_007030 NP_008961
Function May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. {ECO:0000269|PubMed:17105200, ECO:0000269|PubMed:17693641, ECO:0000269|PubMed:18028908}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:10083737}.

TPPP CRISPR/Cas9 KO Plasmid (h) - sc-405957 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP HDR Plasmid (h) - sc-405957-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP Double Nickase Plasmid (h) - sc-405957-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP Double Nickase Plasmid (h2) - sc-405957-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP CRISPR Activation Plasmid (h) - sc-405957-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP CRISPR Activation Plasmid (h2) - sc-405957-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP Lentiviral Activation Particles (h) - sc-405957-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP Lentiviral Activation Particles (h2) - sc-405957-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TPPP siRNA (h) - sc-76720 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPPP shRNA Plasmid (h) - sc-76720-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPPP shRNA (h) Lentiviral Particles - sc-76720-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TPPP/p25 RNAi - H00011076-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU123861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21875 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21875 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TPPP siRNA (Human) - CRH7573 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPPP - MBS8230044 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TPPP (NM_007030.2) - SHH433408 from Creative biogene

Category siRNA
Species Reactivities Human

Human TPPP siRNA - orb268075 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TPPP shRNA Plasmid (Human) - CHH7573 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TPPP miRNA 3'UTR clone - MiUTR1H-10678 from Creative biogene

Species Reactivities Human
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