ITGB4

Gene Symbol	ITGB4
Entrez Gene	3691
Alt Symbol	CD104
Species	Human
Gene Type	protein-coding
Description	integrin, beta 4
Other Description	CD104 antigen|GP150|integrin beta-4|integrin beta-4 subunit
Swissprots	O15339 O14691 A0AVL6 Q0VF97 O15341 O15340 P16144 Q9UIQ4 O14690
Accessions	AAB65422 AAC51632 AAC51633 AAC51634 CAB61345 EAW89305 EAW89306 EAW89307 EAW89308 EAW89309 EAW89310 EAW89311 EAW89312 EAW89313 EAW89314 EAW89315 P16144 AB208913 BAD92150 AF011375 AAB65421 AI318403 AK304792 BAG65542 AK310952 BC109238 AAI09239 BC118916 AAI18917 BC126411 AAI26412 BC143738 AAI43739 BC143742 AAI43743 CA391583 X51841 CAA36134 X52186 CAA36433 X53587 CAA37656 XM_005257309 XP_005257366 XM_005257311 XP_005257368 XM_005257312 XP_005257369 XM_006721866 XP_006721929 XM_006721867 XP_006721930 XM_006721868 XP_006721931 XM_006721870 XP_006721933 XM_011524751 XP_011523053 XM_011524752 XP_011523054 NM_000213 NP_000204 NM_001005619 NP_001005619 NM_001005731 NP_001005731
Function	Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. {ECO:0000269|PubMed:12482924, ECO:0000269|PubMed:19403692}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes.
Tissue Specificity	Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
Top Pathways	Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat ITGB4 / Integrin Beta 4 ELISA Kit (Cell-Based ELISA) - LS-F2084 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-ITGB4 / Integrin Beta 4 (Tyr1510) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1402 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Human ITGB4 / Integrin Beta 4 ELISA Kit (Sandwich ELISA) - LS-F8203 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Integrin _4 (ITG _4/CD104), Human, ELISA Kit - CSB-E13913h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Integrin Beta 4 (ITGb4), Human, ELISA Kit - SEB440Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.055ng/mL Range 0.156-10ng/mL

Integrin beta4 Colorimetric Cell-Based ELISA Kit - CB5372 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Integrin beta4 (Phospho-Tyr1510) Colorimetric Cell-Based ELISA Kit - CBP1427 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Integrin Beta 4 (ITGb4), ELISA Kit - MBS2018874 from MyBioSource Category ELISA Kit Prices $355.00, $540.00, $730.00, $2,985.00, $5,410.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of ITGb4 is typically less than 0.057ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL. The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.312ng/mL, 0.156ng/mL.

integrin, beta 4, ELISA Kit - MBS702767 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Integrin Beta 4 (ITGb4) - SEB440Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human integrin β4(ITG β4/CD104) ELISA Kit - CSB-E13913h from Cusabio Category ELISA Kit Sensitivity Request Information Range Request Information

ELISA Kit for Integrin Beta 4 (ITGb4) - SEB440Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Integrin Beta 4 (ITGb4), Human, ELISA Kit - DL-ITGb4-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human ITGb4 ELISA Kit - abx571350 from Abbexa Category ELISA Kit Sensitivity 0.055 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human ITGB4 ELISA Kit - E020123 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of ITGb4 is typically less than 0.057ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding tw

Integrin Beta 4 (ITGb4), ELISA Kit - MBS451290 from MyBioSource Category ELISA Kit Prices $400.00, $530.00, $2,325.00, $4,515.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.055ng/mL Range 0.156-10ng/mL

Search more