Gene Symbol | CST5 |
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Entrez Gene | 1473 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystatin D |
Other Description | cystatin 5|cystatin-5|cystatin-D|cysteine-proteinase inhibitor |
Swissprots | Q5JRF5 Q9UCA0 P28325 |
Accessions | CAA42590 EAX10132 P28325 BC062678 AAH62678 BC069514 AAH69514 CB985957 HQ447459 ADQ31945 X70377 CAA49838 NM_001900 NP_001891 |
Function | Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. {ECO:0000269|PubMed:8083219}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:20189825}. |
Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall bladder tissue. {ECO:0000269|PubMed:20189825}. |
Top Pathways | Salivary secretion |
cystatin D (F-3) - sc-398553 from Santa Cruz Biotechnology
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cystatin D (C-18) - sc-46889 from Santa Cruz Biotechnology
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cystatin D (H-52) - sc-368123 from Santa Cruz Biotechnology
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cystatin D (N-19) - sc-46890 from Santa Cruz Biotechnology
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Anti-Cystatin D antibody - ab69706 from Abcam
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Anti-CST5 Antibody (C-Terminus) - LS-C112803 from LifeSpan Bioscience
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Anti-CST5 Antibody (aa30-148) - LS-C184216 from LifeSpan Bioscience
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Anti-CST5 Antibody - LS-C307113 from LifeSpan Bioscience
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Anti-CST5 Antibody (aa21-142) - LS-C315011 from LifeSpan Bioscience
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Cystatin D/Cst5 Antibody - AF1202 from Novus Biologicals
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Cystatin D/Cst5 Antibody - NBP2-31852 from Novus Biologicals
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Cystatin D/Cst5 Antibody - H00001473-B01P from Novus Biologicals
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Cystatin D/Cst5 Antibody (MM0230-4K33) - NBP2-12250 from Novus Biologicals
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Cystatin D/Cst5 Antibody [Biotin] - BAF1202 from Novus Biologicals
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Cystatin D Polyclonal Antibody - bs-9215R from Bioss
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Anti-CST5 antibody produced in mouse - SAB1405671 from Sigma-Aldrich
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Anti-CST5 antibody produced in rabbit - HPA061449 from Sigma-Aldrich
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Cystatin D antibody [4K33] - GTX52683 from GeneTex
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Human Cystatin D Biotinylated Antibody - BAF1202 from R&D Systems
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Human Cystatin D Antibody - MAB1202 from R&D Systems
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Human Cystatin D MAb (Clone 206006), Mouse IgG2A - MAB1202-SP from R&D Systems
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Human Cystatin D Antibody - AF1202 from R&D Systems
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Human Cystatin D Affinity Purified Polyclonal Ab, Goat IgG - AF1202-SP from R&D Systems
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Anti -CST5 (Cystatin-5, Cystatin-D) - 125418 from USBiological Life Science
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Anti -Cystatin D - 216436 from USBiological Life Science
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