Gene Symbol | CST5 |
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Entrez Gene | 1473 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystatin D |
Other Description | cystatin 5|cystatin-5|cystatin-D|cysteine-proteinase inhibitor |
Swissprots | Q5JRF5 Q9UCA0 P28325 |
Accessions | CAA42590 EAX10132 P28325 BC062678 AAH62678 BC069514 AAH69514 CB985957 HQ447459 ADQ31945 X70377 CAA49838 NM_001900 NP_001891 |
Function | Cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. {ECO:0000269|PubMed:8083219}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:20189825}. |
Tissue Specificity | Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in parotid gland but not in seminal vesicle, prostate, epididymis, testis, ovary, placenta, thyroid, gastric corpus, small intestine, liver, or gall bladder tissue. {ECO:0000269|PubMed:20189825}. |
Top Pathways | Salivary secretion |
CST5-Over-expression-Lysate - LY11901a from Abgent, a WuXi AppTec company
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CST5 293T Cell Transient Overexpression Lysate(Denatured) - H00001473-T01 from Acris Antibodies
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CST5 overexpression lysate - LY419667 from Acris Antibodies
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Cystatin D/Cst5 Overexpression Lysate (Denatured) - H00001473-T01 from Novus Biologicals
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Human Cystatin D / CST5 HEK293 Cell Lysate (WB positive control) - 10506-H08HL-300 from Sino Biological
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Human CST5 Human Cells Transfected Lysate (positive control) (denatured) - orb172836 from Biorbyt
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Cystatin D/Cst5 Overexpression Lysate (Native) - NBP2-10785 from Novus Biologicals
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Panoply™ Human CST5 Knockdown Stable Cell Line - CSC-DC003742 from Creative biogene
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