Gene Symbol | ZGPAT |
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Entrez Gene | 84619 |
Alt Symbol | GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, CCCH-type with G patch domain |
Other Description | g patch domain-containing protein 6|zinc finger CCCH domain-containing protein 9|zinc finger CCCH-type with G patch domain-containing protein|zinc finger and G patch domain-containing protein |
Swissprots | E1P5K1 Q8N5A5 Q5JWI9 Q96JI0 Q96JU4 Q9H401 Q5JWJ0 Q8NC55 Q4VXN9 Q8WUV4 |
Accessions | EAW75220 EAW75221 EAW75222 EAW75223 EAW75224 EAW75225 EAW75226 EAW75227 EAW75228 EAW75229 Q8N5A5 AB058750 BAB47476 AK027878 BAB55426 AK074961 BAC11317 AK307368 AK314726 BC019338 AAH19338 BC032612 AAH32612 CV027894 DA055150 DA252406 DA848516 DB025637 HQ448238 ADQ32718 NM_181484 NM_001083113 NP_001076582 NM_001195653 NP_001182582 NM_001195654 NP_001182583 NM_032527 NP_115916 NM_181485 NP_852150 |
Function | Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. {ECO:0000269|PubMed:19644445}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19644445}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:19644445}. |
ZGPAT protein (His-DHFR tag) - ab127524 from Abcam
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ZGPAT Antibody Blocking Peptide - LS-E15719 from LifeSpan Bioscience
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ZGPAT Antibody Blocking Peptide - LS-E15718 from LifeSpan Bioscience
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ZGPAT Antibody Blocking Peptide - LS-E15734 from LifeSpan Bioscience
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ZGPAT Antibody Blocking Peptide - LS-E31203 from LifeSpan Bioscience
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ZGPAT Blocking Peptide - 33R-5187 from Fitzgerald
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ZGPAT Blocking Peptide - 33R-1898 from Fitzgerald
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ZGPAT Blocking Peptide - 33R-1217 from Fitzgerald
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ZGPAT (C-term) Control Peptide - AP55580CP-N from Acris Antibodies
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ZGPAT Peptide - 6611P from ProSci
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ZGPAT fusion protein - ag19420 from Proteintech Group
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ZGPAT fusion protein - ag19620 from Proteintech Group
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Recombinant Human Zinc finger CCCH-type with G patch domain-containing protein(Z - CSB-YP836668HU CSB-EP836668HU CSB-BP836668HU CSB-MP836668HU from Cusabio
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ZGPAT (transcript variant 3) - TP321260 from Acris Antibodies
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Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) , Recombinant Protein - MBS1387732 from MyBioSource
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ZGPAT Protein - NBP1-92609PEP from Novus Biologicals
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ZGPAT Peptide, Human - M34GP17824H from Creative Peptides
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ZGPAT Recombinant Protein Antigen - NBP2-55609PEP from Novus Biologicals
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