Gene Symbol | ZGPAT |
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Entrez Gene | 84619 |
Alt Symbol | GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, CCCH-type with G patch domain |
Other Description | g patch domain-containing protein 6|zinc finger CCCH domain-containing protein 9|zinc finger CCCH-type with G patch domain-containing protein|zinc finger and G patch domain-containing protein |
Swissprots | E1P5K1 Q8N5A5 Q5JWI9 Q96JI0 Q96JU4 Q9H401 Q5JWJ0 Q8NC55 Q4VXN9 Q8WUV4 |
Accessions | EAW75220 EAW75221 EAW75222 EAW75223 EAW75224 EAW75225 EAW75226 EAW75227 EAW75228 EAW75229 Q8N5A5 AB058750 BAB47476 AK027878 BAB55426 AK074961 BAC11317 AK307368 AK314726 BC019338 AAH19338 BC032612 AAH32612 CV027894 DA055150 DA252406 DA848516 DB025637 HQ448238 ADQ32718 NM_181484 NM_001083113 NP_001076582 NM_001195653 NP_001182582 NM_001195654 NP_001182583 NM_032527 NP_115916 NM_181485 NP_852150 |
Function | Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. {ECO:0000269|PubMed:19644445}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19644445}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:19644445}. |
ZGPAT (F-15) - sc-86032 from Santa Cruz Biotechnology
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ZGPAT (N-16) - sc-86033 from Santa Cruz Biotechnology
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Anti-ZGPAT antibody - ab108533 from Abcam
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Anti-ZGPAT antibody - ab105661 from Abcam
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Anti-ZGPAT antibody - ab105662 from Abcam
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Anti-ZGPAT antibody - ab105663 from Abcam
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Anti-ZGPAT Antibody (N-Terminus) IHC-plus⢠- LS-B10315 from LifeSpan Bioscience
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Anti-ZGPAT Antibody (aa254-303) IHC-plus⢠- LS-B10854 from LifeSpan Bioscience
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Anti-ZGPAT Antibody - LS-C178451 from LifeSpan Bioscience
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Anti-ZGPAT Antibody (C-Terminus) - LS-C80521 from LifeSpan Bioscience
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Anti-ZGPAT Antibody (C-Terminus) IHC-plus⢠- LS-B9602 from LifeSpan Bioscience
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ZGPAT Antibody - NBP1-56562 from Novus Biologicals
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ZGPAT Antibody - NBP1-56561 from Novus Biologicals
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ZGPAT Antibody - NBP1-92609 from Novus Biologicals
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ZGPAT Antibody - NBP1-56937 from Novus Biologicals
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Anti-ZGPAT (498-510) antibody produced in rabbit - SAB1102857 from Sigma-Aldrich
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Anti-ZGPAT (ab3) antibody produced in rabbit - SAB2102781 from Sigma-Aldrich
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Anti-ZGPAT antibody produced in rabbit - HPA043248 from Sigma-Aldrich
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Anti-ZGPAT (ab2) antibody produced in rabbit - SAB2102780 from Sigma-Aldrich
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Anti-ZGPAT (361-375) antibody produced in rabbit - SAB1102856 from Sigma-Aldrich
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ZGPAT antibody - N-terminal region (ARP42679_P050) - ARP42679_P050 from Aviva Systems Biology
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ZGPAT antibody - C-terminal region (ARP42680_P050) - ARP42680_P050 from Aviva Systems Biology
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ZGPAT antibody - middle region (ARP42725_P050) - ARP42725_P050 from Aviva Systems Biology
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ZGPAT antibody - orb77905 from Biorbyt
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ZGPAT antibody - 70R-3509 from Fitzgerald
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