RRAGC

Gene Symbol RRAGC
Entrez Gene 64121
Alt Symbol GTR2, RAGC, TIB929
Species Human
Gene Type protein-coding
Description Ras-related GTP binding C
Other Description GTPase-interacting protein 2|Rag C protein|ras-related GTP-binding protein C
Swissprots Q9H202 Q9H8Q8 Q9HB90
Accessions EAX07293 EAX07294 Q9HB90 AF131773 AF272035 AAG32662 AF323609 AAG45221 AK023373 BAB14548 AK092808 AK298573 BAG60765 AK298788 BAG60926 AK315791 AW327252 BC016668 AAH16668 BG717489 BI461665 BQ003663 CA449149 CB132041 CX761032 DQ891734 ABM82660 DQ894911 ABM85837 ES308561 HY202961 HY264464 NM_001271851 NP_001258780 NM_022157 NP_071440
Function Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. {ECO:0000269|PubMed:20381137}.
Subcellular Location Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
Top Pathways mTOR signaling pathway

RagC (D31G9) XP ® Rabbit mAb - 5466 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D31G9
Western blot analysis of extracts from various cell lines using RagC (D31G9) XP ® Rabbit mAb.

RagC Antibody - 3360 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using RagC Antibody.

RagC (D8H5) Rabbit mAb - 9480 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8H5
Western blot analysis of extracts from various cell lines using RagC (D8H5) Rabbit mAb.

Anti-RRAGC antibody - ab168819 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RRAGC antibody (ab168819) at 0.1 µg/mlLane 1 : 293T whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : Jurkat whole cell lysateLane 4 : TCMK-1 whole cell lysateLane 5 : NIH3T3 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-RRAGC antibody - ab187705 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1: Immunoprecipitation from 293T whole cell lysate (0.5 - 1 mg for IP, 20% of IP loaded), using ab187705 at 6 µg per reaction.Lane 2: Immunoprecipitation from 293T whole cell lysate (0.5 - 1 mg for IP, 20% of IP loaded), using Control IgG.Subsequent Western blot detection used ab187705 at 1 µg/ml.

Anti-RRAGC antibody - ab171425 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RRAGC antibody (ab171425) at 1/100 dilutionLane 1 : 293 cell line lysateLane 2 : MDA-MB231 cell line lysateLane 3 : HeLa cell line lysateLane 4 : HepG2 cell line lysateLysates/proteins at 35 µg per lane.

Anti-RRAGC antibody - ab102547 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RRAGC antibody (ab102547) at 1 µg/ml + A549 cell lysate at 10 µg

Anti-RRAGC antibody - ab138028 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RRAGC antibody (ab138028) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-RRAGC antibody [2938C3a] - ab76577 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2938C3a
Anti-RRAGC antibody [2938C3a] (ab76577) at 2 µg/ml + immunising recombinant protein

Anti-RRAGC / RAGC Antibody (N-Terminus) - LS-C126237 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-RRAGC / RAGC Antibody (N-Terminus) - LS-C131951 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-RRAGC / RAGC Antibody (clone 2938C3a) - LS-C184712 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2938C3a

Anti-RRAGC / RAGC Antibody (aa169-198, AP) - LS-C240255 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa169-198, APC) - LS-C240256 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa169-198, Biotin) - LS-C240257 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa169-198, FITC) - LS-C240258 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa169-198, PE) - LS-C240259 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa266-315) - LS-C200631 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using RRAGC antibody.

Anti-RRAGC / RAGC Antibody (aa169-198, Azide-free, HRP) - LS-C248052 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa168-198) - LS-C324832 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa349-399) - LS-C290938 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RRAGC / RAGC Antibody (aa71-120) - LS-C116710 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RRAGC antibody LS-C116710 Western blot of A549 cell lysate.

Anti-RRAGC / RAGC Antibody (aa302-351) - LS-C120304 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-RRAGC / RAGC Antibody (aa1-50) - LS-C290937 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse RRAGC by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-RRAGC antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-RRAGC / RAGC Antibody (aa1-50) - LS-C290666 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human RagC by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-RagC antibody used for IP at 6 ug/mg lysate. RagC was also immunoprecipitated by rabbit anti-RagC antibody BL14630. For blotting immunoprecipitated RagC, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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