RRAGC

Gene Symbol	RRAGC
Entrez Gene	64121
Alt Symbol	GTR2, RAGC, TIB929
Species	Human
Gene Type	protein-coding
Description	Ras-related GTP binding C
Other Description	GTPase-interacting protein 2|Rag C protein|ras-related GTP-binding protein C
Swissprots	Q9H202 Q9H8Q8 Q9HB90
Accessions	EAX07293 EAX07294 Q9HB90 AF131773 AF272035 AAG32662 AF323609 AAG45221 AK023373 BAB14548 AK092808 AK298573 BAG60765 AK298788 BAG60926 AK315791 AW327252 BC016668 AAH16668 BG717489 BI461665 BQ003663 CA449149 CB132041 CX761032 DQ891734 ABM82660 DQ894911 ABM85837 ES308561 HY202961 HY264464 NM_001271851 NP_001258780 NM_022157 NP_071440
Function	Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. {ECO:0000269|PubMed:20381137}.
Subcellular Location	Cytoplasm. Nucleus. Lysosome. Note=Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
Top Pathways	mTOR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rag C CRISPR/Cas9 KO Plasmid (h) - sc-412984 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C HDR Plasmid (h) - sc-412984-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C Double Nickase Plasmid (h) - sc-412984-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C Double Nickase Plasmid (h2) - sc-412984-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C CRISPR Activation Plasmid (h) - sc-412984-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C CRISPR Activation Plasmid (h2) - sc-412984-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C Lentiviral Activation Particles (h) - sc-412984-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C Lentiviral Activation Particles (h2) - sc-412984-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Rag C siRNA (h) - sc-88543 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag C shRNA Plasmid (h) - sc-88543-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Rag C shRNA (h) Lentiviral Particles - sc-88543-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RRAGC RNAi - H00064121-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU011561 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18678 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18678 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01109 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr01109

RRAGC siRNA (Human) - CRJ1933 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGC - MBS8220549 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human RRAGC (NM_022157.2) - SHH399868 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human RRAGC(NM_022157.2) - SHR198678 from Creative biogene Category siRNA Species Reactivities Human

Human RRAGC siRNA - orb272434 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

RRAGC shRNA Plasmid (Human) - CHJ1933 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

RRAGC miRNA 3'UTR clone - MiUTR1H-09041 from Creative biogene Species Reactivities Human

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