DNAAF1

Gene Symbol	DNAAF1
Entrez Gene	123872
Alt Symbol	CILD13, LRRC50, ODA7
Species	Human
Gene Type	protein-coding
Description	dynein, axonemal, assembly factor 1
Other Description	dynein assembly factor 1, axonemal|leucine rich repeat containing 50|leucine-rich repeat-containing protein 50|outer row dynein assembly 7 homolog
Swissprots	Q96MB6 Q69YJ0 Q8NEP3 Q69YI8 Q69YW5 Q96LP3 B4DJA3
Accessions	EAW95500 EAW95501 Q8NEP3 AK057238 BAB71392 AK058059 BAB71645 AK295990 BAG58765 AK310961 AL137334 CAH10706 AL833327 AL833328 CAH10390 AL833336 CAH10394 BC024009 AAH24009 BX648657 DA349893 XM_006721129 XP_006721192 XM_011522850 XP_011521152 XM_011522851 XP_011521153 XM_011522852 XP_011521154 XM_011522853 XP_011521155 XM_011522854 XP_011521156 XM_011522855 XP_011521157 XM_011522856 XP_011521158 XM_011522857 XP_011521159 XM_011522858 XP_011521160 XM_011522859 XP_011521161 XM_011522860 XP_011521162 NM_178452 NP_848547
Function	Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. {ECO:0000269|PubMed:18385425, ECO:0000269|PubMed:19944400, ECO:0000269|PubMed:19944405}.
Subcellular Location	Cell projection, cilium {ECO:0000269|PubMed:18385425}. Cytoplasm {ECO:0000269|PubMed:18385425}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:18385425}. Note=In HEK293T cells, it is diffusely cytoplasmic and concentrates at the mitotic spindle poles, while in MDCK cells, it localizes in the cilium. In vivo, this protein is probably restricted to the cilium.
Tissue Specificity	Mainly expressed in trachea and testis. {ECO:0000269|PubMed:19944405}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNAAF1 overexpression lysate - LY405926 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LRRC50 293 Cell Lysate - 403764 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

LRRC50 Overexpression Lysate (Native) - NBL1-12700 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

LRRC50 Over-expression Lysate Product - GWB-E49490 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human DNAAF1 Knockdown Stable Cell Line - CSC-DC004382 from Creative biogene Category Cell Line Species Human

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