DNAAF1

Gene Symbol DNAAF1
Entrez Gene 123872
Alt Symbol CILD13, LRRC50, ODA7
Species Human
Gene Type protein-coding
Description dynein, axonemal, assembly factor 1
Other Description dynein assembly factor 1, axonemal|leucine rich repeat containing 50|leucine-rich repeat-containing protein 50|outer row dynein assembly 7 homolog
Swissprots Q96MB6 Q69YJ0 Q8NEP3 Q69YI8 Q69YW5 Q96LP3 B4DJA3
Accessions EAW95500 EAW95501 Q8NEP3 AK057238 BAB71392 AK058059 BAB71645 AK295990 BAG58765 AK310961 AL137334 CAH10706 AL833327 AL833328 CAH10390 AL833336 CAH10394 BC024009 AAH24009 BX648657 DA349893 XM_006721129 XP_006721192 XM_011522850 XP_011521152 XM_011522851 XP_011521153 XM_011522852 XP_011521154 XM_011522853 XP_011521155 XM_011522854 XP_011521156 XM_011522855 XP_011521157 XM_011522856 XP_011521158 XM_011522857 XP_011521159 XM_011522858 XP_011521160 XM_011522859 XP_011521161 XM_011522860 XP_011521162 NM_178452 NP_848547
Function Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli. {ECO:0000269|PubMed:18385425, ECO:0000269|PubMed:19944400, ECO:0000269|PubMed:19944405}.
Subcellular Location Cell projection, cilium {ECO:0000269|PubMed:18385425}. Cytoplasm {ECO:0000269|PubMed:18385425}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:18385425}. Note=In HEK293T cells, it is diffusely cytoplasmic and concentrates at the mitotic spindle poles, while in MDCK cells, it localizes in the cilium. In vivo, this protein is probably restricted to the cilium.
Tissue Specificity Mainly expressed in trachea and testis. {ECO:0000269|PubMed:19944405}.

LRRC50 CRISPR/Cas9 KO Plasmid (h) - sc-407107 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 HDR Plasmid (h) - sc-407107-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 Double Nickase Plasmid (h) - sc-407107-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 Double Nickase Plasmid (h2) - sc-407107-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 CRISPR Activation Plasmid (h) - sc-407107-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 CRISPR Activation Plasmid (h2) - sc-407107-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 Lentiviral Activation Particles (h) - sc-407107-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 Lentiviral Activation Particles (h2) - sc-407107-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 siRNA (h) - sc-93420 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC50 shRNA Plasmid (h) - sc-93420-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRC50 shRNA (h) Lentiviral Particles - sc-93420-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN12750 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12750 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNAAF1 siRNA (Human) - CRJ4743 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNAAF1 - MBS8221239 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LRRC50 CRISPR/Cas9 KO Plasmid (h2) - sc-407107-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRC50 HDR Plasmid (h2) - sc-407107-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human Dnaaf1 (NM_178452.4) - SHH279049 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human LRRC50(NM_178452.4) - SHH163307 from Creative biogene

Category siRNA
Species Reactivities Human

Human DNAAF1 siRNA - orb275244 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNAAF1 shRNA Plasmid (Human) - CHJ4743 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DNAAF1 miRNA 3'UTR clone - MiUTR1H-05924 from Creative biogene

Species Reactivities Human
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