| Gene Symbol |
DDAH1
|
| Entrez Gene |
23576
|
| Alt Symbol |
DDAH, HEL-S-16
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dimethylarginine dimethylaminohydrolase 1
|
| Other Description |
DDAH-1|DDAHI|N(G),N(G)-dimethylarginine dimethylaminohydrolase 1|NG, NG-dimethylarginine dimethylaminohydrolase|dimethylargininase-1|epididymis secretory protein Li 16
|
| Swissprots |
Q86XK5 O94760 Q5HYC8
|
| Accessions |
EAW73199 EAW73200 EAW73201 EAW73202 O94760 AK024917 AK026093 AK055626 AK098405 AK294752 BAG57891 AK302531 BAG63803 AK304876 BAG65613 AK309225 AK312432 BAG35341 AW051386 BC033680 AAH33680 BC036432 BC043235 AAH43235 BX648145 CAI45988 DC324361 EU794605 ACJ13659 XM_005270707 XP_005270764 XM_005270709 XP_005270766 XM_005270710 XP_005270767 XM_006710544 XP_006710607 XM_011541158 XP_011539460 NM_001134445 NP_001127917 NM_012137 NP_036269
|
| Function |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
|
| Tissue Specificity |
Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. {ECO:0000269|PubMed:10493931}.
|