Gene Symbol | DDAH1 |
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Entrez Gene | 23576 |
Alt Symbol | DDAH, HEL-S-16 |
Species | Human |
Gene Type | protein-coding |
Description | dimethylarginine dimethylaminohydrolase 1 |
Other Description | DDAH-1|DDAHI|N(G),N(G)-dimethylarginine dimethylaminohydrolase 1|NG, NG-dimethylarginine dimethylaminohydrolase|dimethylargininase-1|epididymis secretory protein Li 16 |
Swissprots | Q86XK5 O94760 Q5HYC8 |
Accessions | EAW73199 EAW73200 EAW73201 EAW73202 O94760 AK024917 AK026093 AK055626 AK098405 AK294752 BAG57891 AK302531 BAG63803 AK304876 BAG65613 AK309225 AK312432 BAG35341 AW051386 BC033680 AAH33680 BC036432 BC043235 AAH43235 BX648145 CAI45988 DC324361 EU794605 ACJ13659 XM_005270707 XP_005270764 XM_005270709 XP_005270766 XM_005270710 XP_005270767 XM_006710544 XP_006710607 XM_011541158 XP_011539460 NM_001134445 NP_001127917 NM_012137 NP_036269 |
Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
Tissue Specificity | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. {ECO:0000269|PubMed:10493931}. |
DDAH I CRISPR/Cas9 KO Plasmid (h) - sc-402719 from Santa Cruz Biotechnology
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DDAH I HDR Plasmid (h) - sc-402719-HDR from Santa Cruz Biotechnology
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DDAH I Double Nickase Plasmid (h) - sc-402719-NIC from Santa Cruz Biotechnology
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DDAH I Double Nickase Plasmid (h2) - sc-402719-NIC-2 from Santa Cruz Biotechnology
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DDAH I CRISPR Activation Plasmid (h) - sc-402719-ACT from Santa Cruz Biotechnology
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DDAH I CRISPR Activation Plasmid (h2) - sc-402719-ACT-2 from Santa Cruz Biotechnology
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DDAH I Lentiviral Activation Particles (h) - sc-402719-LAC from Santa Cruz Biotechnology
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DDAH I Lentiviral Activation Particles (h2) - sc-402719-LAC-2 from Santa Cruz Biotechnology
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DDAH I siRNA (h) - sc-105276 from Santa Cruz Biotechnology
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DDAH I shRNA Plasmid (h) - sc-105276-SH from Santa Cruz Biotechnology
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DDAH I shRNA (h) Lentiviral Particles - sc-105276-V from Santa Cruz Biotechnology
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Dimethylarginine Dimethylaminohydrolase 1/DDAH1 RNAi - H00023576-R01 from Novus Biologicals
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MISSION® esiRNA - EHU134331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7018 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7018 from Sigma-Aldrich
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DDAH1 siRNA (Human) - CRH8370 from Cohesion Biosciences
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DDAH1 - MBS8201664 from MyBioSource
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shRNA set against Human DDAH1 (NM_012137.3) - SHH275541 from Creative biogene
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DDAH1 shRNA Plasmid (Human) - CHH8370 from Cohesion Biosciences
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