Gene Symbol | GUCY2D |
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Entrez Gene | 3000 |
Alt Symbol | CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC |
Species | Human |
Gene Type | protein-coding |
Description | guanylate cyclase 2D, membrane (retina-specific) |
Other Description | ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, retinal|retinal guanylate cyclase 1|retinal guanylyl cyclase 1|rod outer segment membrane guanylate cyclase |
Swissprots | Q02846 Q6LEA7 |
Accessions | AAA60366 CAA10914 EAW90103 Q02846 BC148421 AAI48422 BM931704 DQ426876 ABD90536 M92432 AAA60547 XM_011523816 XP_011522118 NM_000180 NP_000171 |
Function | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells. |
Top Pathways | Olfactory transduction, Phototransduction, Purine metabolism |
ROS-GC1 (B-7) - sc-376217 from Santa Cruz Biotechnology
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ROS-GC1 (H-225) - sc-50512 from Santa Cruz Biotechnology
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ROS-GC1 (C-13) - sc-34521 from Santa Cruz Biotechnology
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ROS-GC1 (S-17) - sc-34523 from Santa Cruz Biotechnology
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ROS-GC1 (A-17) - sc-34520 from Santa Cruz Biotechnology
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Anti-PGCD antibody - ab55224 from Abcam
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Anti-GUCY2D Antibody (aa540-570, PE) - LS-C258192 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570, AP) - LS-C259642 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570, Biotin) - LS-C259643 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570, APC) - LS-C259644 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570, Azide-free, HRP) - LS-C259646 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570, FITC) - LS-C259645 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa547-578) - LS-C321848 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (clone 4E12) - LS-C197388 from LifeSpan Bioscience
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Anti-GUCY2D Antibody (aa540-570) - LS-C166743 from LifeSpan Bioscience
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GUCY2D Antibody (7E5.) - H00003000-M07 from Novus Biologicals
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GUCY2D Antibody (1E6.) - H00003000-M06 from Novus Biologicals
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GUCY2D Antibody (6E9) - H00003000-M03 from Novus Biologicals
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GUCY2D Antibody (1F12) - H00003000-M08 from Novus Biologicals
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GUCY2D Antibody (4E12.) - H00003000-M01 from Novus Biologicals
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GUCY2D Antibody (5E10) - H00003000-M05 from Novus Biologicals
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GUCY2D Antibody (6D9) - H00003000-M02 from Novus Biologicals
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GUCY2D Antibody (X1) - H00003000-M09 from Novus Biologicals
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GUCY2D Antibody - H00003000-A01 from Novus Biologicals
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GUCY2D Antibody (7B6) - H00003000-M04A from Novus Biologicals
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