GUCY2D

Gene Symbol	GUCY2D
Entrez Gene	3000
Alt Symbol	CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC
Species	Human
Gene Type	protein-coding
Description	guanylate cyclase 2D, membrane (retina-specific)
Other Description	ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, retinal|retinal guanylate cyclase 1|retinal guanylyl cyclase 1|rod outer segment membrane guanylate cyclase
Swissprots	Q02846 Q6LEA7
Accessions	AAA60366 CAA10914 EAW90103 Q02846 BC148421 AAI48422 BM931704 DQ426876 ABD90536 M92432 AAA60547 XM_011523816 XP_011522118 NM_000180 NP_000171
Function	Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells.
Top Pathways	Olfactory transduction, Phototransduction, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

ROS-GC1 CRISPR/Cas9 KO Plasmid (h) - sc-404483 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 HDR Plasmid (h) - sc-404483-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 Double Nickase Plasmid (h) - sc-404483-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 Double Nickase Plasmid (h2) - sc-404483-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 CRISPR Activation Plasmid (h) - sc-404483-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 CRISPR Activation Plasmid (h2) - sc-404483-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 Lentiviral Activation Particles (h) - sc-404483-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 Lentiviral Activation Particles (h2) - sc-404483-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 siRNA (h) - sc-45429 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ROS-GC1 shRNA Plasmid (h) - sc-45429-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ROS-GC1 shRNA (h) Lentiviral Particles - sc-45429-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

GUCY2D RNAi - H00003000-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® siRNA - SIHK0880 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0879 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK0878 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1641 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1641 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

GUCY2D siRNA (Human) - CRH2035 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GUCY2D - MBS8232617 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ROS-GC1 CRISPR/Cas9 KO Plasmid (h2) - sc-404483-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ROS-GC1 HDR Plasmid (h2) - sc-404483-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human GUCY2D (NM_000180.3) - SHH309378 from Creative biogene Category siRNA Species Reactivities Human

Human GUCY2D siRNA - orb262537 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

GUCY2D shRNA Plasmid (Human) - CHH2035 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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