Gene Symbol | GUCY2D |
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Entrez Gene | 3000 |
Alt Symbol | CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC |
Species | Human |
Gene Type | protein-coding |
Description | guanylate cyclase 2D, membrane (retina-specific) |
Other Description | ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, retinal|retinal guanylate cyclase 1|retinal guanylyl cyclase 1|rod outer segment membrane guanylate cyclase |
Swissprots | Q02846 Q6LEA7 |
Accessions | AAA60366 CAA10914 EAW90103 Q02846 BC148421 AAI48422 BM931704 DQ426876 ABD90536 M92432 AAA60547 XM_011523816 XP_011522118 NM_000180 NP_000171 |
Function | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells. |
Top Pathways | Olfactory transduction, Phototransduction, Purine metabolism |
GUCY2D Antibody Blocking Peptide - LS-E1078 from LifeSpan Bioscience
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Recombinant Human GUCY2D Protein - H00003000-Q01 from Novus Biologicals
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GUCY2D-Antibody-Center-Blocking-peptide - BP11569c from Abgent, a WuXi AppTec company
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GUCY2D / RETGC1 - H00003000-Q01-10 from Acris Antibodies
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GUCY2D / RETGC1 - H00003000-Q01-25 from Acris Antibodies
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GUCY2D / RETGC1 - TP318368 from Acris Antibodies
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GUCY2D Peptide, Human - M34GP06777H from Creative Peptides
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GUCY2D, Recombinant Protein - MBS1491639 from MyBioSource
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