| Gene Symbol | GUCY2D |
|---|---|
| Entrez Gene | 3000 |
| Alt Symbol | CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanylate cyclase 2D, membrane (retina-specific) |
| Other Description | ROS-GC|cone rod dystrophy 6|guanylate cyclase 2D, retinal|retinal guanylate cyclase 1|retinal guanylyl cyclase 1|rod outer segment membrane guanylate cyclase |
| Swissprots | Q02846 Q6LEA7 |
| Accessions | AAA60366 CAA10914 EAW90103 Q02846 BC148421 AAI48422 BM931704 DQ426876 ABD90536 M92432 AAA60547 XM_011523816 XP_011522118 NM_000180 NP_000171 |
| Function | Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells. |
| Top Pathways | Olfactory transduction, Phototransduction, Purine metabolism |