ERCC1

Gene Symbol	ERCC1
Entrez Gene	2067
Alt Symbol	COFS4, RAD10, UV20
Species	Human
Gene Type	protein-coding
Description	excision repair cross-complementation group 1
Other Description	DNA excision repair protein ERCC-1|excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Swissprots	Q96S40 P07992 B2RC01 Q7Z7F5 B3KRR0
Accessions	AAA52395 AAM34796 EAW57348 EAW57349 EAW57350 P07992 AA761510 AB069681 BAB62810 AF001925 AAC16253 AF433652 AAL56574 AK092039 BAG52472 AK314884 BAG37398 BC008930 AAH08930 BC052813 AAH52813 BM011724 BM450988 BM789972 BQ019990 BQ671113 BT019806 AAV38609 BU627436 DB468563 DQ586988 DQ893002 ABM83928 DQ896248 ABM87247 M13194 AAA52394 M28650 AAA35810 S94539 AAD14434 XM_005258634 XP_005258691 XM_005258635 XP_005258692 XM_005258636 XP_005258693 XM_005258637 XP_005258694 XM_011526610 XP_011524912 NM_001166049 NP_001159521 NM_001983 NP_001974 NM_202001 NP_973730
Function	Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Subcellular Location	Isoform 3: Nucleus.
Top Pathways	Nucleotide excision repair, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ERCC1-Over-expression-Lysate - LY12535a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ERCC1 overexpression lysate - LY404356 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ERCC1 293 Cell Lysate - 403340 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ERCC1 293 Cell Lysate - 409173 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ERCC1 Overexpression Lysate (Native) - NBL1-10319 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ERCC1 Overexpression Lysate (Native) - NBL1-10318 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ERCC1 (h): 293T Lysate - sc-116554 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

ERCC1 Over-expression Lysate Product - GWB-8BDEC7 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ERCC1 Over-expression Lysate Product - GWB-3AB235 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ERCC1 Overexpression Lysate (Denatured) - H00002067-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ERCC1-knockout Cell lysate - LC810072 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human ERCC1 Knockdown Stable Cell Line - CSC-DC005033 from Creative biogene Category Cell Line Species Human

Human ERCC1 Knockout Cell Line-HeLa - CSC-RT0506 from Creative biogene Category Cell Line Species Human

ERCC1 KO Cell Lysate-HeLa - CLKO-0011 from Creative biogene Category Cell Lysate

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