ERCC1

Gene Symbol ERCC1
Entrez Gene 2067
Alt Symbol COFS4, RAD10, UV20
Species Human
Gene Type protein-coding
Description excision repair cross-complementation group 1
Other Description DNA excision repair protein ERCC-1|excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Swissprots Q96S40 P07992 B2RC01 Q7Z7F5 B3KRR0
Accessions AAA52395 AAM34796 EAW57348 EAW57349 EAW57350 P07992 AA761510 AB069681 BAB62810 AF001925 AAC16253 AF433652 AAL56574 AK092039 BAG52472 AK314884 BAG37398 BC008930 AAH08930 BC052813 AAH52813 BM011724 BM450988 BM789972 BQ019990 BQ671113 BT019806 AAV38609 BU627436 DB468563 DQ586988 DQ893002 ABM83928 DQ896248 ABM87247 M13194 AAA52394 M28650 AAA35810 S94539 AAD14434 XM_005258634 XP_005258691 XM_005258635 XP_005258692 XM_005258636 XP_005258693 XM_005258637 XP_005258694 XM_011526610 XP_011524912 NM_001166049 NP_001159521 NM_001983 NP_001974 NM_202001 NP_973730
Function Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Subcellular Location Isoform 3: Nucleus.
Top Pathways Nucleotide excision repair, Fanconi anemia pathway

SignalSilence ® ERCC1 siRNA I - 8896 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® ERCC1 siRNA I (+), using ERCC1 (D61F5) Rabbit mAb #5437 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The ERCC1 (D61F5) Rabbit mAb confirms silencing of ERCC1 expression while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

ERCC1 CRISPR/Cas9 KO Plasmid (h) - sc-400630 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 HDR Plasmid (h) - sc-400630-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 Double Nickase Plasmid (h) - sc-400630-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 Double Nickase Plasmid (h2) - sc-400630-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 CRISPR Activation Plasmid (h) - sc-400630-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 CRISPR Activation Plasmid (h2) - sc-400630-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 Lentiviral Activation Particles (h) - sc-400630-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 Lentiviral Activation Particles (h2) - sc-400630-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERCC1 siRNA (h2) - sc-270369 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERCC1 shRNA Plasmid (h2) - sc-270369-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERCC1 shRNA (h2) Lentiviral Particles - sc-270369-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERCC1 RNAi - H00002067-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU156971 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1434 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1433 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1435 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1433 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1434 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1435 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ERCC1 siRNA (Human) - CRH1442 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC1 RNAi - H00002067-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ERCC1 - MBS8200396 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human ERCC1 siRNA - orb261944 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERCC1 shRNA Plasmid (Human) - CHH1442 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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