ARL6

Gene Symbol	ARL6
Entrez Gene	84100
Alt Symbol	BBS3, RP55
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor-like 6
Other Description	ADP-ribosylation factor-like protein 6|Bardet-Biedl syndrome 3 protein
Swissprots	Q9H0F7 D3DN31 A8KA93
Accessions	EAW79880 EAW79881 EAW79882 EAW79883 EAW79884 Q9H0F7 AK292958 BAF85647 AK310829 AK311281 AL136815 CAB66749 AL138043 AM392662 CAL37540 AM393355 CAL38233 BC024239 AAH24239 BG722744 BM705017 BU183949 BU607306 DC323603 XM_006713779 XP_006713842 XM_006713783 XP_006713846 XM_011513230 XP_011511532 XR_924184 XR_924185 XR_924186 XR_924187 XR_924188 XR_924189 NM_001278293 NP_001265222 NM_032146 NP_115522 NM_177976 NP_816931 NR_103511
Function	Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity). {ECO:0000250|UniProtKB:O88848, ECO:0000269|PubMed:20207729, ECO:0000269|PubMed:20603001, ECO:0000269|PubMed:22072986}.
Subcellular Location	Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Appears in a pattern of punctae flanking the microtubule axoneme that likely correspond to small membrane-associated patches. Localizes to the so-called ciliary gate where vesicles carrying ciliary cargo fuse with the membrane.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BBS3 (C-13) - sc-49794 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

BBS3 (C-5) - sc-390021 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

BBS3 (A-14) - sc-49793 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

BBS3 (H-120) - sc-134558 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-ARL6 antibody - ab167185 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ARL6 antibody - ab55821 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ARL6 Antibody (N-Terminus) IHC-plus™ - LS-B2142 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ARL6 Antibody (Internal) - LS-C154817 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

ARL6 Antibody - NBP1-40022 from Novus Biologicals Prices $329.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

ARL6 Antibody - H00084100-A01 from Novus Biologicals Host Mouse Clonality Polyclonal

ARL6 Antibody - H00084100-B01P-50ug from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-ARL6 antibody produced in mouse - SAB1412895 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse

Anti-ARL6 antibody produced in rabbit - HPA019361 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ARL6-Antibody-N-term - AP2309a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

ARL6 Antibody (OALA02455) - OALA02455 from Aviva Systems Biology Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-ARL6 Antibody - AC11-0222 from Abcore Prices $325.00 Sizes 100 µg Host Goat Clonality Polyclonal

ARL6 antibody - 70R-15830 from Fitzgerald Prices $375.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

ARL6 antibody - 12676-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

ARL6 (N-term) antibody - AP08505PU-N from Acris Antibodies Prices $430.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

ARL6 antibody - H00084100-A01 from Acris Antibodies Prices $300.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Rabbit Anti-Human ARL6 (N-Terminus) - 119-12768 from RayBiotech Host Rabbit

Rabbit Anti-Human ARL6 (N-term) - 102-15020 from RayBiotech Host Rabbit

ARL6 Antibody - 49-766 from ProSci Prices $375.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

BBS3 antibody - 12676-1-AP from Proteintech Group Prices $279.00 Sizes con: 50 μg/150μl Host Rabbit Clonality Polyclonal

ARL6 Antibody - 35639 from Signalway Antibody Prices $279.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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