ARL6

Gene Symbol	ARL6
Entrez Gene	84100
Alt Symbol	BBS3, RP55
Species	Human
Gene Type	protein-coding
Description	ADP-ribosylation factor-like 6
Other Description	ADP-ribosylation factor-like protein 6|Bardet-Biedl syndrome 3 protein
Swissprots	Q9H0F7 D3DN31 A8KA93
Accessions	EAW79880 EAW79881 EAW79882 EAW79883 EAW79884 Q9H0F7 AK292958 BAF85647 AK310829 AK311281 AL136815 CAB66749 AL138043 AM392662 CAL37540 AM393355 CAL38233 BC024239 AAH24239 BG722744 BM705017 BU183949 BU607306 DC323603 XM_006713779 XP_006713842 XM_006713783 XP_006713846 XM_011513230 XP_011511532 XR_924184 XR_924185 XR_924186 XR_924187 XR_924188 XR_924189 NM_001278293 NP_001265222 NM_032146 NP_115522 NM_177976 NP_816931 NR_103511
Function	Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity). {ECO:0000250|UniProtKB:O88848, ECO:0000269|PubMed:20207729, ECO:0000269|PubMed:20603001, ECO:0000269|PubMed:22072986}.
Subcellular Location	Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Appears in a pattern of punctae flanking the microtubule axoneme that likely correspond to small membrane-associated patches. Localizes to the so-called ciliary gate where vesicles carrying ciliary cargo fuse with the membrane.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ARL6 full length protein - ab108125 from Abcam Category Protein Prices $235.00, $866.00 Sizes 50 µg, 250 µg Source E. coli Species Human

ARL6-Antibody-N-term-Blocking-Peptide - BP2309a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARL6 (1-186, His-tag) - AR39024PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

ARL6 (1-186, His-tag) - AR39024PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

ARL6, 1-186aa, Human, His tag, E.coli - 01-1904-6 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

BBS3 fusion protein - Ag3363 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ARL6, 1-186aa, Recombinant Protein - GWB-P0954E from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human ARL6, His-tagged - ARL6-26185TH from Creative Biomart Category Protein Source E. coli

Recombinant Human ARL6, His-tagged - ARL6-3544H from Creative Biomart Category Protein Source E. coli.

Recombinant Human ADP-Ribosylation Factor-Like 6, His-tagged - ARL6-4974H from Creative Biomart Category Protein Source Human

ARL6 1-186aa - CMB-917 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 50.00 µg, 250.00 µg Source E.coli Species Human

Recombinant Human ADP-ribosylation factor-like protein 6(ARL6) - CSB-YP887945HU CSB-EP887945HU CSB-BP887945HU CSB-MP887945HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ARL6, 1-186aa, Human, His tag, E.coli - ATGP1084 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

ADP-Ribosylation Factor-Like 6 - MBS144515 from MyBioSource Category Protein Prices $140.00, $205.00, $4,975.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

ADP-ribosylation factor-like protein 6 (ARL6) - MBS1425231 from MyBioSource Category Protein Prices $1,390.00, $1,390.00, $1,845.00, $1,845.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ARL6 Protein - abx163585 from Abbexa Category Protein Species Human, Rat

ARL6 (transcript variant 1) - TP305966 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARL6 (transcript variant 2) - TP313584 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ARL6, Recombinant Protein - MBS204065 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

ARL6-Antibody-C-term-Blocking-Peptide - BP2309b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ARL6 - PAT-81124-1 from Nordic BioSite Category Protein Species Human

ARL6 - PAT-81124-2 from Nordic BioSite Category Protein Species Human

Human ARL6 protein - orb54492 from Biorbyt Category Protein Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00 Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg Species Human

ARL6 Recombinant Protein (Human) (OPCA04979) - OPCA04979 from Aviva Systems Biology Category Protein Species Human

BBS3 fusion protein - Ag27788 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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