HCAR1

Gene Symbol	HCAR1
Entrez Gene	27198
Alt Symbol	FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR, TAGPCR
Species	Human
Gene Type	protein-coding
Description	hydroxycarboxylic acid receptor 1
Other Description	G protein-coupled receptor 104|G protein-coupled receptor 81|G-protein coupled receptor 104|G-protein coupled receptor 81|T-cell activation G protein-coupled receptor|hydroxy-carboxylic acid receptor 1|lactate receptor 1
Swissprots	B2R9X4 Q9BXC0 Q6NXU5 Q3Y5J3 Q4VBN1
Accessions	AAL26481 AAZ67915 BAB89344 BAC06084 EAW98337 Q9BXC0 AF345568 AAK29071 AF385431 AAM43832 AF385432 AAM43833 AK122659 AK289557 BAF82246 AK313955 BAG36671 AY507143 AAR92485 BC066881 AAH66881 BC066882 AAH66882 BC066883 AAH66883 BC067484 AAH67484 BC095506 AAH95506 EU809458 ACJ03844 GQ129267 ACT64401 GQ129268 ACT64402 NM_032554 NP_115943
Function	Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. {ECO:0000269|PubMed:19047060}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus. {ECO:0000269|PubMed:11574155, ECO:0000269|PubMed:19047060}.
Top Pathways	cAMP signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E4006 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FKSG80 / GPR81 Blocking Peptide - LS-E28491 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E28490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E28488 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E28492 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E27090 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPR81-Antibody-C-term-Blocking-Peptide - BP16232b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR81 blocking peptide - GTX88409-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Pig

GPR81 Blocking Peptide - abx063821 from Abbexa Category Peptide Species Human, Mouse, Rat

GPCR GPR81 Peptide - AC21-1912-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GPR81 - H00027198-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

GPR81 - H00027198-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GPR81 - H00027198-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GPR81 Peptide - 42-015P from ProSci Category Peptide Species Human

GPR81 fusion protein - Ag13682 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GPR81 fusion protein - ag13669 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human GPR81, GST-tagged - GPR81-13490H from Creative Biomart Category Protein Source E.coli Species Human

GPR81 Blocking Peptide - CBP2627 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

GPR81 Peptide - BS60353P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human GPR81 Protein - H00027198-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

FKSG80 / GPR81 Antibody Blocking Peptide - LS-E39738 from LifeSpan Bioscience Category Peptide Prices $100.00 Sizes 50 µg

GPR81/FKSG80, Peptide - MBS425147 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog, Pig

GPR81-C322-Blocking-Peptide - BP6361c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR81-Blocking-Peptide - BP6361b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR81-Blocking-Peptide - BP6361a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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