KNTC1

Gene Symbol KNTC1
Entrez Gene 9735
Alt Symbol ROD
Species Human
Gene Type protein-coding
Description kinetochore associated 1
Other Description Rough Deal homolog, centromere/kinetochore protein|kinetochore-associated protein 1
Swissprots B3KSG2 A7E2C4 P50748
Accessions EAW98333 EAW98334 P50748 AA157787 AI916095 AK093470 BAG52724 AK293403 BAG56910 AK303337 BAG64400 BC055410 BC150278 AAI50279 D79988 BAA11483 XM_006719706 XP_006719769 XM_011539027 XP_011537329 XM_011539028 XP_011537330 XM_011539029 XP_011537331 XM_011539030 XP_011537332 XR_944844 XR_944845 XR_944846 NM_014708 NP_055523
Function Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. {ECO:0000269|PubMed:11146660, ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15824131}.
Subcellular Location Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Dynamic pattern of localization during the cell cycle. At interphase, uniformly distributed throughout the cytoplasm and nucleus. By prophase and until late stages of prometaphase, a fraction of the total pool is concentrated at kinetochores. By metaphase, detected at kinetochores, along spindle fibers and most prominently at the poles. By late anaphase until the end of telophase, no longer detectable on kinetochores or along spindle fibers, but still present at the spindle poles.
Tissue Specificity High expression in testis.

ROD (V-16) - sc-66597 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ROD (C-14) - sc-66594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ROD (43-K) - sc-81853 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ROD (43-K): sc-81853. Western blot analysis of ROD expression in HeLa nuclear extract.

Anti-Kinetochore antibody - ab85996 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Kinetochore antibody (ab85996) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-Kinetochore antibody - ab56745 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Kinetochore antibody - ab97841 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Kinetochore antibody (ab97841) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR3 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-KNTC1 / ROD Antibody (aa2100-2209) - LS-C308686 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-KNTC1 / ROD Antibody (aa375-425) - LS-C288497 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KNTC1 / ROD Antibody (aa2159-2209) - LS-C288500 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KNTC1 / ROD Antibody (aa2100-2210, Azide-free) - LS-C330498 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-KNTC1 / ROD Antibody (N-Terminus) - LS-C107491 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KNTC1 antibody LS-C107491 Western blot of OVCAR-3 cell lysate.

KNTC1 Antibody (10H4) - H00009735-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10H4
Western Blot: KNTC1 Antibody (10H4) [H00009735-M01] - KNTC1 monoclonal antibody (M01), clone 10H4 Analysis of KNTC1 expression in Hela S3 NE.

KNTC1 Antibody - NB100-88130 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: KNTC1 Antibody [NB100-88130] - Detection of Human ROD/KNTC1 on HeLa whole cell lysate using NB100-88130. ROD/KNTC1 was also immunoprecipitated by rabbit anti-ROD/KNTC1 antibody NBN100-88131.

KNTC1 Antibody - NBP1-83032 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: KNTC1 Antibody [NBP1-83032] - Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & actin filaments.

KNTC1 Antibody - NB100-88131 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: KNTC1 Antibody [NB100-88131] - Detection of Human ROD/KNTC1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ROD/KNTC1 antibody NB100-88131 used for IP at 3 mcg/mg lysate. ROD/KNTC1 was also immunoprecipitated by rabbit anti-ROD/KNTC1 antibody NB100-88130, which recognizes an upstream epitope. Detection: Chemiluminescence with an exposure time of 10 seconds. (Lower bands that were immunoprecipitated by both NB100-88130 and NB100-88131 are marked by asterisks.)

KNTC1 Antibody - H00009735-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

KNTC1 Polyclonal Antibody - bs-7808R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KNTC1, (N-terminal) antibody produced in rabbit - SAB2104695 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KNTC1, antibody produced in rabbit: <B>Cat. No. SAB2104695</B>: Immunoblotting analysis of KNTC1 in OVCAR-3 cell lysate with KNTC1 anitbody at 1 μg/mL.

Monoclonal Anti-KNTC1 antibody produced in mouse - WH0009735M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10H4
<B>Immunoblotting</B><BR/>Monoclonal Anti-KNTC1, <B>Cat. No. WH0009735M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~250.7 kDa using Hela NE lysate.

Anti-KNTC1 antibody produced in rabbit - HPA025241 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KNTC1: <B>Cat. No. HPA025241</B>: Immunohistochemical staining of human vagina shows strong cytoplasmic and nuclear positivity in most squamous epithelial cells.

Monoclonal Anti-KNTC1, (C-terminal) antibody produced in mouse - SAB1404753 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10D9
<B>Immunoblotting</B><BR/>Monoclonal Anti-KNTC1: <B>Cat. No. SAB1404753</B>: Antibody concentration: 1 μg/mL. Specific band of ~38.2 kDa using immunogen protein lysate.

KNTC1 antibody - N-terminal region (ARP33708_P050) - ARP33708_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KNTC1-Antibody-monoclonal-M01 - AT2645a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10H4
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .

KNTC1-antibody-N-terminal-region - AI10101 from Abgent, a WuXi AppTec company

Prices $293.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KNTC1 antibody - N-terminal region (AI10101) in Human OVCAR-3 cells using Western BlotWB Suggested Anti-KNTC1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: OVCAR-3 cell lysateKNTC1 is supported by BioGPS gene expression data to be expressed in OVCAR3

PDE6 beta antibody [N3C2], Internal - GTX109709 from GeneTex

Host Rabbit
Clonality Polyclonal
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