Gene Symbol | DUSP23 |
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Entrez Gene | 54935 |
Alt Symbol | DUSP25, LDP-3, MOSP, VHZ |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 23 |
Other Description | VH1-like member Z|VH1-like phosphatase Z|dual specificity protein phosphatase 23|low molecular mass dual specificity phosphatase 3|low-molecular-mass dual-specificity phosphatase 3 |
Swissprots | Q9NX48 Q9BVJ7 |
Accessions | CAD44455 EAW52775 Q9BVJ7 AB164404 BAD12141 AF086553 AK000449 BAA91172 BC001140 AAH01140 JF432846 ADZ16063 XM_005245289 XP_005245346 NM_017823 NP_060293 |
Function | Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). {ECO:0000269|PubMed:15147733, ECO:0000269|PubMed:15201283}. |
Subcellular Location | Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic. Also nuclear. |
Tissue Specificity | Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach. {ECO:0000269|PubMed:15147733, ECO:0000269|PubMed:15201283}. |
DUSP23 (N-13) - sc-79455 from Santa Cruz Biotechnology
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Anti-DUSP23 antibody - ab154505 from Abcam
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Anti-DUSP23 antibody - ab150524 from Abcam
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Anti-DUSP23 antibody - ab61566 from Abcam
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Anti-DUSP23 antibody - ab37338 from Abcam
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Anti-DUSP23 Antibody (clone 3C10) - LS-C173535 from LifeSpan Bioscience
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Anti-DUSP23 Antibody (Internal) IHC-plus⢠- LS-A6803 from LifeSpan Bioscience
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Anti-DUSP23 Antibody - LS-C310189 from LifeSpan Bioscience
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Anti-DUSP23 Antibody (Internal) IHC-plus⢠- LS-A6806 from LifeSpan Bioscience
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DUSP23 Antibody - NBP2-16240 from Novus Biologicals
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DUSP23 Antibody - NB110-40452 from Novus Biologicals
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DUSP23 Antibody - H00054935-D01P from Novus Biologicals
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Anti-DUSP23 antibody produced in rabbit - SAB1411016 from Sigma-Aldrich
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Anti-DUSP23 antibody produced in rabbit - HPA045792 from Sigma-Aldrich
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Anti-DUSP23 antibody produced in chicken - GW21550 from Sigma-Aldrich
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DUSP23 antibody - GTX70953 from GeneTex
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DUSP23 antibody - 10R-3923 from Fitzgerald
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Anti -DUSP23 (Dual Specificity Phosphatase 23, FLJ20442) - D9840-66A from USBiological Life Science
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DUSP23 Antibody (OALA01091) - OALA01091 from Aviva Systems Biology
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DUSP23 Antibody (OALA01092) - OALA01092 from Aviva Systems Biology
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DUSP23 (Internal) antibody - AP07002PU-N from Acris Antibodies
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DUSP23 antibody - SP4137P from Acris Antibodies
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DUSP23 antibody - H00054935-D01P from Acris Antibodies
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Rabbit Anti-Human DUSP23 (Internal) - 119-10219 from RayBiotech
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Rabbit Anti-Human DUSP23 (Internal) - 119-11057 from RayBiotech
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