SH3BP5

Gene Symbol SH3BP5
Entrez Gene 9467
Alt Symbol SAB, SH3BP-5
Species Human
Gene Type protein-coding
Description SH3-domain binding protein 5 (BTK-associated)
Other Description SH3 domain-binding protein 5|SH3 domain-binding protein that preferentially associates with BTK
Swissprots Q5JWV9 B3KQW6 O60239
Accessions EAW64225 EAW64226 EAW64227 EAW64228 O60239 AA843106 AB005047 BAA25922 AK090524 BAG52178 AK313167 BAG35985 AL117422 CAI46220 AW673562 BC006169 BC010123 AAH10123 BC023195 BG475051 BP308415 BX114836 BX641159 CAE46071 CA429664 CN402267 DA530463 DQ892875 ABM83801 EU176725 ABW03526 XM_011534251 XP_011532553 XM_011534252 XP_011532554 XM_011534253 XP_011532555 XM_011534254 XP_011532556 NM_001018009 NP_001018009 NM_004844 NP_004835
Function Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. {ECO:0000269|PubMed:10339589, ECO:0000269|PubMed:9571151}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:12167088}.
Tissue Specificity Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate. {ECO:0000269|PubMed:9571151}.

Sab CRISPR/Cas9 KO Plasmid (h) - sc-405461 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab HDR Plasmid (h) - sc-405461-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab Double Nickase Plasmid (h) - sc-405461-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab Double Nickase Plasmid (h2) - sc-405461-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab CRISPR Activation Plasmid (h) - sc-405461-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab CRISPR Activation Plasmid (h2) - sc-405461-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab Lentiviral Activation Particles (h) - sc-405461-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab Lentiviral Activation Particles (h2) - sc-405461-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sab siRNA (h) - sc-106528 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sab shRNA Plasmid (h) - sc-106528-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sab shRNA (h) Lentiviral Particles - sc-106528-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SH3BP5 RNAi - H00009467-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SH3BP5 RNAi - H00009467-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU018391 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19264 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19264 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08695 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08695

SH3BP5 siRNA (Human) - CRH6283 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SH3BP5 - MBS8210530 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SH3BP5 shRNA Plasmid (Human) - CHH6283 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SH3BP5 miRNA 3'UTR clone - MiUTR3H-07835 from Creative biogene

Species Reactivities Human

SH3BP5 miRNA 3'UTR clone - MiUTR3H-07836 from Creative biogene

Species Reactivities Human
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