B3GAT3

Gene Symbol B3GAT3
Entrez Gene 26229
Alt Symbol GLCATI, glcUAT-I
Species Human
Gene Type protein-coding
Description beta-1,3-glucuronyltransferase 3
Other Description Sqv-8-like protein|UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase|beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Swissprots B7ZAB3 Q9UEP0 Q96I06 O94766
Accessions EAW74042 EAW74043 EAW74044 O94766 AB009598 BAA34537 AJ005865 CAA06742 AK075166 AK297970 BAG60280 AK310200 AK316228 BAH14599 BC007906 AAH07906 BC011173 BC019832 AAH19832 BC071961 AAH71961 HQ447823 ADQ32307 XM_011544936 XP_011543238 NM_001288721 NP_001275650 NM_001288722 NP_001275651 NM_001288723 NP_001275652 NM_012200 NP_036332 NR_109991
Function Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP- GlcUA) during completion of linkage region formation. {ECO:0000269|PubMed:24425863}.
Subcellular Location Golgi apparatus membrane {ECO:0000269|PubMed:21763480}; Single-pass type II membrane protein {ECO:0000269|PubMed:21763480}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:21763480}.
Tissue Specificity Ubiquitous (but weakly expressed in all tissues examined).
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Human B3GAT3 full length protein - ab161932 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab161932 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human B3GAT3 protein fragment - ab156962 from Abcam

Category Protein
Prices $297.00
Sizes 100 µg
Source E. coli
Species Human
15% SDS-PAGE analysis of ab156962 (3 µg).

Human B3GAT3 protein fragment - ab161933 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab161933 on a 12.5% SDS-PAGE stained with Coomassie Blue.

B3GAT3 Antibody Blocking Peptide - LS-E1377 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

B3GAT3 Antibody Blocking Peptide - LS-E17049 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

beta-1,3-Glucuronyltransferase 3/B3GAT3 Recombinant Protein - H00026229-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

beta-1,3-Glucuronyltransferase 3/B3GAT3 Partial Recombinant Protein - H00026229-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human beta-1,3-Glucuronyltransferase 3/B3GAT3 Protein - NBP2-22712 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Source E.coli
Species Human
SDS-Page: B3GAT3 Protein [NBP2-22712]

B3GAT3-Antibody-C-term-Blocking-peptide - BP12032b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human B3GAT3, CF - 6808-GT-020 from R&D Systems

Category Protein
Source E. coli-derived, Glu72-Val335, with an N-terminal Met and 6-His tag

B3GAT3 (His Tag) protein - orb171530 from Biorbyt

Category Protein
Prices $298.00, $400.00
Sizes 10 μg, 20 μg
Source E. coli
Species Human
SDS-PAGE analysis of B3GAT3 (His Tag) protein

Human B3GAT3 protein - orb191419 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Source Escherichia Coli.
Species Human

B3GAT3 Blocking Peptide - 33R-7265 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

B3GAT3 protein (His tag) - 80R-2819 from Fitzgerald

Category Protein
Prices $275.00
Sizes 100 µg
Source E.coli

B3GAT3 (29-335, His-tag) - AR50938PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
B3GAT3

B3GAT3 (29-335, His-tag) - AR50938PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
B3GAT3

B3GAT3 - H00026229-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

B3GAT3 - H00026229-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

B3GAT3 - H00026229-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

B3GAT3 - H00026229-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

B3GAT3, 29-335aa, Human, His tag, E.coli - 01-P2114 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

B3GAT3 Recombinant Protein - 96-043 from ProSci

Category Protein
Prices $375.00
Sizes 100 µg
Source E. coli
Species Human
The purity of rh B3GAT3 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

B3GAT3 fusion protein - ag9296 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

B3GAT3 fusion protein - Ag8362 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human B3GAT3, His-tagged - B3GAT3-7603H from Creative Biomart

Category Protein
Source E. coli
Species Human
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