B3GAT3

Gene Symbol	B3GAT3
Entrez Gene	26229
Alt Symbol	GLCATI, glcUAT-I
Species	Human
Gene Type	protein-coding
Description	beta-1,3-glucuronyltransferase 3
Other Description	Sqv-8-like protein|UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase|beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Swissprots	B7ZAB3 Q9UEP0 Q96I06 O94766
Accessions	EAW74042 EAW74043 EAW74044 O94766 AB009598 BAA34537 AJ005865 CAA06742 AK075166 AK297970 BAG60280 AK310200 AK316228 BAH14599 BC007906 AAH07906 BC011173 BC019832 AAH19832 BC071961 AAH71961 HQ447823 ADQ32307 XM_011544936 XP_011543238 NM_001288721 NP_001275650 NM_001288722 NP_001275651 NM_001288723 NP_001275652 NM_012200 NP_036332 NR_109991
Function	Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP- GlcUA) during completion of linkage region formation. {ECO:0000269|PubMed:24425863}.
Subcellular Location	Golgi apparatus membrane {ECO:0000269|PubMed:21763480}; Single-pass type II membrane protein {ECO:0000269|PubMed:21763480}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:21763480}.
Tissue Specificity	Ubiquitous (but weakly expressed in all tissues examined).
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GlcAT-I (D-7) - sc-390475 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

GlcAT-I (H-5) - sc-390526 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

GlcAT-I (C-12) - sc-240515 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GlcAT-I (K-17) - sc-240514 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-B3GAT3 antibody - ab68026 from Abcam Prices $359.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-B3GAT3 antibody - ab103081 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 antibody - C-terminal - ab170795 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, AP) - LS-C233041 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, PE) - LS-C233048 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, APC) - LS-C233043 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, Biotin) - LS-C233042 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, FITC) - LS-C233044 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321, Azide-free, HRP) - LS-C249500 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody - LS-C306470 from LifeSpan Bioscience Prices $455.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-B3GAT3 Antibody - LS-C309566 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa300-329) - LS-C319737 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (clone 1C11) - LS-C139355 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1C11

Anti-B3GAT3 Antibody (aa35-84) - LS-C116334 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-B3GAT3 Antibody (aa293-321) - LS-C156709 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody - NBP2-33611 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody - NBP1-59853 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody - H00026229-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody - H00026229-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody (4C12) - H00026229-M01 from Novus Biologicals Host Mouse Clonality Monoclonal Clone 4C12

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody (1C11) - H00026229-M02 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1C11

Search more