EHD2

Gene Symbol EHD2
Entrez Gene 30846
Alt Symbol PAST2
Species Human
Gene Type protein-coding
Description EH-domain containing 2
Other Description EH domain containing 2|EH domain-containing protein 2|PAST homolog 2
Swissprots Q9NZN4 B2RDH9 Q96CB6 B4DNU6
Accessions CAF06404 EAW57505 EAW57506 Q9NZN4 AF181263 AAF40470 AF454952 AAL51078 AK026134 AK074701 BAC11147 AK097126 AK097228 BAG53436 AK293429 BAG56934 AK296907 BAG59463 AK298067 BAG60358 AK300512 BAG62224 AK301380 BAH13468 AK315548 BAG37926 AK316448 BAH14819 BC014445 AAH14445 BG677716 DA094880 DB260808 DQ892835 ABM83761 DQ896082 ABM87081 NM_014601 NP_055416
Function Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17233914}; Peripheral membrane protein {ECO:0000269|PubMed:17233914}; Cytoplasmic side {ECO:0000269|PubMed:17233914}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
Top Pathways Endocytosis

EHD2 CRISPR/Cas9 KO Plasmid (h) - sc-403776 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 HDR Plasmid (h) - sc-403776-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 Double Nickase Plasmid (h) - sc-403776-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 Double Nickase Plasmid (h2) - sc-403776-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 CRISPR Activation Plasmid (h) - sc-403776-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 CRISPR Activation Plasmid (h2) - sc-403776-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 Lentiviral Activation Particles (h) - sc-403776-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 Lentiviral Activation Particles (h2) - sc-403776-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EHD2 siRNA (h) - sc-40517 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EHD2 shRNA Plasmid (h) - sc-40517-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EHD2 shRNA (h) Lentiviral Particles - sc-40517-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU056831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7723 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7723 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EHD2 siRNA (Human) - CRH9357 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EHD2 RNAi - H00030846-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

EHD2 - MBS8214567 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EHD2 (NM_014601.3) - SHH283985 from Creative biogene

Category siRNA
Species Reactivities Human

EHD2 shRNA Plasmid (Human) - CHH9357 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EHD2 miRNA 3'UTR clone - MiUTR3H-08022 from Creative biogene

Species Reactivities Human
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