DAZL

Gene Symbol DAZL
Entrez Gene 1618
Alt Symbol DAZH, DAZL1, DAZLA, SPGYLA
Species Human
Gene Type protein-coding
Description deleted in azoospermia-like
Other Description DAZ homolog|DAZ-like autosomal|SPGY-like-autosomal|deleted in azoospermia-like 1|germline specific RNA binding protein|spermatogenesis gene on the Y-like autosomal
Swissprots O15396 Q5HYB4 Q92904 Q92909
Accessions AAB84361 ABK58591 CBH19255 EAW64278 EAW64279 Q92904 AK303026 BAG64152 AK310341 BC027595 AAH27595 BX648638 CAI45996 DB080081 DQ576044 EU176226 ABW03677 U65918 AAC50813 U66078 AAB63596 U66726 AAB39935 NM_001190811 NP_001177740 NM_001351 NP_001342
Function RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. {ECO:0000250}.
Tissue Specificity Testis specific. {ECO:0000269|PubMed:8896558, ECO:0000269|PubMed:8968755, ECO:0000269|PubMed:8968756}.

DAZL Antibody - 8042 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and human testes tissue using DAZL Antibody.

DAZL (D2A4) Rabbit mAb (IHC Specific) - 13057 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (100 sections)
Host Rabbit
Clonality Monoclonal
Clone D2A4
Immunohistochemical analysis of paraffin-embedded mouse testes (left) and mouse kidney (right) using DAZL (D2A4) Rabbit mAb (IHC Specific). As expected, kidney is DAZL negative.

DAZL (E-6) - sc-390929 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DAZL (E-6): sc-390929. Western blot analysis of DAZL expression in human testis (A) and mouse testis (B) tissue extracts.

DAZL (C-20) - sc-27333 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAZL (C-20): sc-27333. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts and cytoplasmic staining of Leydig cells.

DAZL (H-90) - sc-366304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DAZL (H-90): sc-366304. Western blot analysis of DAZL expression in mouse testis tissue extract.

Anti-DAZL antibody - ab128238 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DAZL antibody [EPR5140] - ab108372 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5140
All lanes : Anti-DAZL antibody [EPR5140] (ab108372) at 1/1000 dilutionLane 1 : Human testis lysateLane 2 : Human small intestine lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-DAZL Antibody (C-Terminus) - LS-C121717 from LifeSpan Bioscience

Prices $755.00
Sizes 2 ml
Host Mouse
Clonality Monoclonal

Anti-DAZL Antibody (aa218-267) - LS-C80318 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-DAZL Antibody (Internal) - LS-C153430 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DAZL Antibody - LS-C47357 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of DAZL in mouse testis lysate. Lane 1 shows pre-immune sera. Lane 2 shows antibody tested at 1:5000 on mouse testis lysate.

Anti-DAZL Antibody (aa281-295, clone 3/11A) - LS-C188293 from LifeSpan Bioscience

Prices $780.00
Sizes 2 ml
Host Mouse
Clonality Monoclonal
Clone 3/11A

Anti-DAZL Antibody (aa50-100) - LS-C190726 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DAZL Antibody (aa260-270) - LS-C54705 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of human ovary lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DAZL Antibody (N-Terminus) - LS-C203263 from LifeSpan Bioscience

Prices $245.00
Sizes 40 µg
Host Rabbit
Clonality Polyclonal

Anti-DAZL Antibody (Internal, clone EPR5140) - LS-C138340 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5140
Western blot analysis on (A) human testis and (B) human small intestine lysates using anti-DAZL antibody.

Anti-DAZL Antibody (aa190-280) - LS-C311438 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DAZL Antibody (C-Terminus) - LS-C201384 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Stomach tumor. DAZL antibody dilution 1.0 ug/ml.

Anti-DAZL Antibody - LS-C331266 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of mouse testis tissue lines, using DAZL antibody.

Anti-DAZL Antibody (aa1-167) IHC-plus™ - LS-B11701 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-DAZL Antibody (aa261-275) - LS-C47444 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

DAZL Antibody - NB100-2437 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: DAZL Antibody [NB100-2437] - Staining of human ovary lysate.

DAZL Antibody - NBP2-23663 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DAZL Antibody [NBP2-23663] - analysis of DAZL in mouse testis lysate. Lane 1 shows pre-immune sera. Lane 2 shows this antibody.

DAZL Antibody - NBP1-85306 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DAZL Antibody [NBP1-85306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

DAZL Antibody - NBP1-85307 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DAZL Antibody [NBP1-85307] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
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