Gene Symbol | DAZL |
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Entrez Gene | 1618 |
Alt Symbol | DAZH, DAZL1, DAZLA, SPGYLA |
Species | Human |
Gene Type | protein-coding |
Description | deleted in azoospermia-like |
Other Description | DAZ homolog|DAZ-like autosomal|SPGY-like-autosomal|deleted in azoospermia-like 1|germline specific RNA binding protein|spermatogenesis gene on the Y-like autosomal |
Swissprots | O15396 Q5HYB4 Q92904 Q92909 |
Accessions | AAB84361 ABK58591 CBH19255 EAW64278 EAW64279 Q92904 AK303026 BAG64152 AK310341 BC027595 AAH27595 BX648638 CAI45996 DB080081 DQ576044 EU176226 ABW03677 U65918 AAC50813 U66078 AAB63596 U66726 AAB39935 NM_001190811 NP_001177740 NM_001351 NP_001342 |
Function | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly cytoplasmic. Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward. {ECO:0000250}. |
Tissue Specificity | Testis specific. {ECO:0000269|PubMed:8896558, ECO:0000269|PubMed:8968755, ECO:0000269|PubMed:8968756}. |
DAZL peptide (240-250) (Carboxyterminal end) - ab45790 from Abcam
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Human DAZL full length protein - ab112279 from Abcam
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Mouse DAZL peptide - ab27733 from Abcam
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DAZL Antibody Blocking Peptide - LS-E14706 from LifeSpan Bioscience
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DAZL Antibody Blocking Peptide - LS-E25917 from LifeSpan Bioscience
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Recombinant Human DAZL Protein - H00001618-P01 from Novus Biologicals
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DAZL blocking peptide - GTX89448-PEP from GeneTex
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DAZL Blocking Peptide - 33R-2778 from Fitzgerald
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DAZL Peptide - AC21-0746-P from Abcore
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DAZL - H00001618-P01 from Acris Antibodies
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DAZL - H00001618-P01-10 from Acris Antibodies
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DAZL - H00001618-P01-25 from Acris Antibodies
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DAZL Peptide - 45-462P from ProSci
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DAZL fusion protein - Ag3326 from Proteintech Group
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Recombinant Human DAZL - DAZL-26122TH from Creative Biomart
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Recombinant Human DAZL, GST-tagged - DAZL-11838H from Creative Biomart
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Recombinant Callithrix jacchus Deleted in azoospermia-like(DAZL) - CSB-YP006514CYL CSB-EP006514CYL CSB-BP006514CYL CSB-MP006514CYL from Cusabio
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Recombinant Human Deleted in azoospermia-like(DAZL) - CSB-YP006514HU CSB-EP006514HU CSB-BP006514HU CSB-MP006514HU from Cusabio
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DAZL - TP305328 from Acris Antibodies
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DAZL, Peptide - MBS425393 from MyBioSource
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DAZL Recombinant Protein Antigen - NBP1-85307PEP from Novus Biologicals
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DAZL Recombinant Protein Antigen - NBP1-85306PEP from Novus Biologicals
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Phospho-DAZLY276-Antibody-Blocking-peptide - BP3640a from Abgent, a WuXi AppTec company
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DAZL-Antibody-Y276-Blocking-Peptide - BP7739d from Abgent, a WuXi AppTec company
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DAZL Peptide, Human - M34GP04039H from Creative Peptides
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