Gene Symbol | INPP4A |
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Entrez Gene | 3631 |
Alt Symbol | INPP4, TVAS1 |
Species | Human |
Gene Type | protein-coding |
Description | inositol polyphosphate-4-phosphatase, type I, 107kDa |
Other Description | inositol polyphosphate-4-phosphatase, type I, 107kD|type I inositol 3,4-bisphosphate 4-phosphatase|type I inositol-3,4-bisphosphate 4-phosphatase |
Swissprots | Q53TD8 Q8TC02 Q96PE3 Q13187 O15326 |
Accessions | AAX93230 EAX01904 EAX01905 EAX01906 EAX01907 EAX01908 EAX01909 EAX01910 Q96PE3 AB462500 AF368319 AAK58870 AK057550 AK091533 AK307823 BC005082 BC028361 AAH28361 DQ895315 ABM86241 U26398 AAB01068 U96919 AAB72150 XM_006712499 XP_006712562 XM_006712500 XP_006712563 XM_006712501 XP_006712564 XM_006712502 XP_006712565 XM_006712503 XP_006712566 XM_006712504 XP_006712567 XM_006712505 XP_006712568 XM_006712506 XP_006712569 XM_006712507 XP_006712570 XM_006712508 XP_006712571 XM_011511122 XP_011509424 XM_011511123 XP_011509425 XM_011511124 XP_011509426 XM_011511125 XP_011509427 XM_011511126 XP_011509428 XM_011511127 XP_011509429 XR_922915 XR_922916 NM_001134224 NP_001127696 NM_001134225 NP_001127697 NM_001566 NP_001557 NM_004027 NP_004018 |
Function | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate. |
Tissue Specificity | Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:11485317}. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Type I 4-phosphatase (D-10) - sc-390550 from Santa Cruz Biotechnology
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Type I 4-phosphatase (E-2) - sc-390549 from Santa Cruz Biotechnology
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Type I 4-phosphatase (A-19) - sc-12315 from Santa Cruz Biotechnology
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Type I 4-phosphatase (N-15) - sc-12314 from Santa Cruz Biotechnology
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Type I 4-phosphatase (H-120) - sc-366306 from Santa Cruz Biotechnology
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Type I 4-phosphatase (S-21) - sc-12316 from Santa Cruz Biotechnology
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Anti-INPP4A antibody - ab126205 from Abcam
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Anti-INPP4A antibody - ab113511 from Abcam
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Anti-INPP4A antibody [EP3425(2)] - ab109622 from Abcam
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Anti-INPP4A antibody [EPR3426] - ab79403 from Abcam
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Anti-INPP4A Antibody (C-Terminus, clone EPR3426) - LS-C105555 from LifeSpan Bioscience
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Anti-INPP4A Antibody (aa601-812) - LS-C178531 from LifeSpan Bioscience
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Anti-INPP4A Antibody (Internal) - LS-C155379 from LifeSpan Bioscience
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Anti-INPP4A Antibody (Internal, clone EP3425(2)) - LS-C138029 from LifeSpan Bioscience
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INPP4A Antibody - NBP1-92023 from Novus Biologicals
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INPP4A Antibody - NBP2-16968 from Novus Biologicals
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Anti-INPP4A antibody produced in rabbit - SAB2700491 from Sigma-Aldrich
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Anti-INPP4A antibody produced in rabbit - HPA001628 from Sigma-Aldrich
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INPP4A-Antibody - AJ1406a from Abgent, a WuXi AppTec company
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INPP4A antibody [EP3425(2)] - GTX62661 from GeneTex
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INPP4A antibody [EPR3426], C-term - GTX62174 from GeneTex
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INPP4A antibody [N2C1], Internal - GTX114498 from GeneTex
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INPP4A antibody - orb77971 from Biorbyt
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INPP4A Antibody - abx038376 from Abbexa
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INPP4A antibody - 12665-1-AP from Proteintech Group
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