| Gene Symbol |
INPP4A
|
| Entrez Gene |
3631
|
| Alt Symbol |
INPP4, TVAS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol polyphosphate-4-phosphatase, type I, 107kDa
|
| Other Description |
inositol polyphosphate-4-phosphatase, type I, 107kD|type I inositol 3,4-bisphosphate 4-phosphatase|type I inositol-3,4-bisphosphate 4-phosphatase
|
| Swissprots |
Q53TD8 Q8TC02 Q96PE3 Q13187 O15326
|
| Accessions |
AAX93230 EAX01904 EAX01905 EAX01906 EAX01907 EAX01908 EAX01909 EAX01910 Q96PE3 AB462500 AF368319 AAK58870 AK057550 AK091533 AK307823 BC005082 BC028361 AAH28361 DQ895315 ABM86241 U26398 AAB01068 U96919 AAB72150 XM_006712499 XP_006712562 XM_006712500 XP_006712563 XM_006712501 XP_006712564 XM_006712502 XP_006712565 XM_006712503 XP_006712566 XM_006712504 XP_006712567 XM_006712505 XP_006712568 XM_006712506 XP_006712569 XM_006712507 XP_006712570 XM_006712508 XP_006712571 XM_011511122 XP_011509424 XM_011511123 XP_011509425 XM_011511124 XP_011509426 XM_011511125 XP_011509427 XM_011511126 XP_011509428 XM_011511127 XP_011509429 XR_922915 XR_922916 NM_001134224 NP_001127696 NM_001134225 NP_001127697 NM_001566 NP_001557 NM_004027 NP_004018
|
| Function |
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate.
|
| Tissue Specificity |
Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:11485317}.
|
| Top Pathways |
Inositol phosphate metabolism, Phosphatidylinositol signaling system
|