Gene Symbol | INPP4A |
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Entrez Gene | 3631 |
Alt Symbol | INPP4, TVAS1 |
Species | Human |
Gene Type | protein-coding |
Description | inositol polyphosphate-4-phosphatase, type I, 107kDa |
Other Description | inositol polyphosphate-4-phosphatase, type I, 107kD|type I inositol 3,4-bisphosphate 4-phosphatase|type I inositol-3,4-bisphosphate 4-phosphatase |
Swissprots | Q53TD8 Q8TC02 Q96PE3 Q13187 O15326 |
Accessions | AAX93230 EAX01904 EAX01905 EAX01906 EAX01907 EAX01908 EAX01909 EAX01910 Q96PE3 AB462500 AF368319 AAK58870 AK057550 AK091533 AK307823 BC005082 BC028361 AAH28361 DQ895315 ABM86241 U26398 AAB01068 U96919 AAB72150 XM_006712499 XP_006712562 XM_006712500 XP_006712563 XM_006712501 XP_006712564 XM_006712502 XP_006712565 XM_006712503 XP_006712566 XM_006712504 XP_006712567 XM_006712505 XP_006712568 XM_006712506 XP_006712569 XM_006712507 XP_006712570 XM_006712508 XP_006712571 XM_011511122 XP_011509424 XM_011511123 XP_011509425 XM_011511124 XP_011509426 XM_011511125 XP_011509427 XM_011511126 XP_011509428 XM_011511127 XP_011509429 XR_922915 XR_922916 NM_001134224 NP_001127696 NM_001134225 NP_001127697 NM_001566 NP_001557 NM_004027 NP_004018 |
Function | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 3,4-bisphosphate. |
Tissue Specificity | Isoform 1 is expressed in the platelets, MEG- 01 megakaryocytes and Jurkat T-cells. Isoform 2 is expressed in the brain. {ECO:0000269|PubMed:11485317}. |
Top Pathways | Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Type I 4-phosphatase CRISPR/Cas9 KO Plasmid (h) - sc-404750 from Santa Cruz Biotechnology
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Type I 4-phosphatase HDR Plasmid (h) - sc-404750-HDR from Santa Cruz Biotechnology
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Type I 4-phosphatase Double Nickase Plasmid (h) - sc-404750-NIC from Santa Cruz Biotechnology
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Type I 4-phosphatase Double Nickase Plasmid (h2) - sc-404750-NIC-2 from Santa Cruz Biotechnology
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Type I 4-phosphatase CRISPR Activation Plasmid (h) - sc-404750-ACT from Santa Cruz Biotechnology
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Type I 4-phosphatase CRISPR Activation Plasmid (h2) - sc-404750-ACT-2 from Santa Cruz Biotechnology
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Type I 4-phosphatase Lentiviral Activation Particles (h) - sc-404750-LAC from Santa Cruz Biotechnology
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Type I 4-phosphatase Lentiviral Activation Particles (h2) - sc-404750-LAC-2 from Santa Cruz Biotechnology
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Type I 4-phosphatase siRNA (h) - sc-44177 from Santa Cruz Biotechnology
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Type I 4-phosphatase shRNA Plasmid (h) - sc-44177-SH from Santa Cruz Biotechnology
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Type I 4-phosphatase shRNA (h) Lentiviral Particles - sc-44177-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU080521 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0263 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0969 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0264 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0262 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0968 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10689 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10689 from Sigma-Aldrich
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INPP4A siRNA (Human) - CRH2434 from Cohesion Biosciences
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INPP4A - MBS8215232 from MyBioSource
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shRNA set against Human INPP4A (NM_001566.2) - SHH319673 from Creative biogene
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Human INPP4A siRNA - orb262936 from Biorbyt
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INPP4A shRNA Plasmid (Human) - CHH2434 from Cohesion Biosciences
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INPP4A miRNA 3'UTR clone - MiUTR3H-03729 from Creative biogene
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