Gene Symbol | SHROOM3 |
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Entrez Gene | 57619 |
Alt Symbol | APXL3, MSTP013, SHRM, ShrmL |
Species | Human |
Gene Type | protein-coding |
Description | shroom family member 3 |
Other Description | F-actin-binding protein|protein Shroom3|shroom-related protein |
Swissprots | Q5QTQ3 Q9P247 Q96IR9 Q6ZRW3 Q8TF72 |
Accessions | EAX05794 EAX05795 Q8TF72 AB040914 BAA96005 AB055660 BAB84689 AF109367 AAQ13515 AK027744 BAB55336 AK055294 AK097800 AK124415 BAC85848 AK127929 BAC87195 AK128677 BAG54709 AK304103 BAG65006 AW025141 BC007291 AAH07291 BC156132 AAI56133 HG496999 XM_005263162 XP_005263219 XM_005263163 XP_005263220 XM_005263164 XP_005263221 XM_005263165 XP_005263222 XM_006714282 XP_006714345 XM_011532157 XP_011530459 XM_011532158 XP_011530460 XM_011532159 XP_011530461 XM_011532160 XP_011530462 XM_011532161 XP_011530463 NM_020859 NP_065910 |
Function | Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, adherens junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with F-actin in stress fibers and adherens junctions. {ECO:0000250}. |
Top Pathways | Tight junction |
Shrm (T-17) - sc-10309 from Santa Cruz Biotechnology
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Shrm (K-19) - sc-10311 from Santa Cruz Biotechnology
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Shrm (E-19) - sc-10310 from Santa Cruz Biotechnology
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ShrmL (A-19) - sc-10308 from Santa Cruz Biotechnology
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Anti-Shroom 3 antibody - ab151009 from Abcam
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Anti-SHROOM3 Antibody (Internal) - LS-C153742 from LifeSpan Bioscience
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SHROOM3 Antibody - NBP2-14617 from Novus Biologicals
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SHROOM3 Antibody - H00057619-B01P-50ug from Novus Biologicals
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Anti-SHROOM3 antibody produced in rabbit - HPA047784 from Sigma-Aldrich
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Anti-SHROOM3 antibody produced in rabbit - SAB3500818 from Sigma-Aldrich
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Anti-SHROOM3 antibody produced in mouse - SAB1412870 from Sigma-Aldrich
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SHROOM3 (Center) antibody - AP55518PU-N from Acris Antibodies
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SHROOM3 antibody - H00057619-B01P from Acris Antibodies
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SHROOM3 Antibody - 7117 from ProSci
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Anti-SHROOM3 (aa 1413-1509) polyclonal antibody - DPABH-03164 from Creative Diagnostics
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Anti-SHROOM3 monoclonal antibody - DCABH-201477 from Creative Diagnostics
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SHROOM3 Polyclonal Antibody - PA5-34482 from Thermo Fisher Scientific
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SHROOM3, Polyclonal Antibody - MBS153584 from MyBioSource
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SHROOM3 Antibody - 600-401-EJ9 from Rockland Immunochemicals Inc
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Shrm (H-61) - sc-367996 from Santa Cruz Biotechnology
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SHROOM3 antibody - pab81549 from Covalab
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SHROOM3-Antibody - ASC11581 from Abgent, a WuXi AppTec company
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SHROOM3 (Center) antibody - TA319988 from Acris Antibodies
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Shroom 3 antibody - orb186128 from Biorbyt
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SHROOM3 Antibody,Biotin conjugated - CSB-PA844740LD01HU from Cusabio
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