Gene Symbol | SHROOM3 |
---|---|
Entrez Gene | 57619 |
Alt Symbol | APXL3, MSTP013, SHRM, ShrmL |
Species | Human |
Gene Type | protein-coding |
Description | shroom family member 3 |
Other Description | F-actin-binding protein|protein Shroom3|shroom-related protein |
Swissprots | Q5QTQ3 Q9P247 Q96IR9 Q6ZRW3 Q8TF72 |
Accessions | EAX05794 EAX05795 Q8TF72 AB040914 BAA96005 AB055660 BAB84689 AF109367 AAQ13515 AK027744 BAB55336 AK055294 AK097800 AK124415 BAC85848 AK127929 BAC87195 AK128677 BAG54709 AK304103 BAG65006 AW025141 BC007291 AAH07291 BC156132 AAI56133 HG496999 XM_005263162 XP_005263219 XM_005263163 XP_005263220 XM_005263164 XP_005263221 XM_005263165 XP_005263222 XM_006714282 XP_006714345 XM_011532157 XP_011530459 XM_011532158 XP_011530460 XM_011532159 XP_011530461 XM_011532160 XP_011530462 XM_011532161 XP_011530463 NM_020859 NP_065910 |
Function | Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, adherens junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Colocalizes with F-actin in stress fibers and adherens junctions. {ECO:0000250}. |
Top Pathways | Tight junction |
Shrm CRISPR/Cas9 KO Plasmid (h) - sc-403640 from Santa Cruz Biotechnology
|
||||||||
Shrm HDR Plasmid (h) - sc-403640-HDR from Santa Cruz Biotechnology
|
||||||||
Shrm Double Nickase Plasmid (h) - sc-403640-NIC from Santa Cruz Biotechnology
|
||||||||
Shrm Double Nickase Plasmid (h2) - sc-403640-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Shrm CRISPR Activation Plasmid (h) - sc-403640-ACT from Santa Cruz Biotechnology
|
||||||||
Shrm CRISPR Activation Plasmid (h2) - sc-403640-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Shrm Lentiviral Activation Particles (h) - sc-403640-LAC from Santa Cruz Biotechnology
|
||||||||
Shrm Lentiviral Activation Particles (h2) - sc-403640-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Shrm siRNA (h) - sc-42248 from Santa Cruz Biotechnology
|
||||||||
Shrm shRNA Plasmid (h) - sc-42248-SH from Santa Cruz Biotechnology
|
||||||||
Shrm shRNA (h) Lentiviral Particles - sc-42248-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU069801 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19317 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19317 from Sigma-Aldrich
|
||||||||
SHROOM3 siRNA (Human) - CRJ1586 from Cohesion Biosciences
|
||||||||
SHROOM3 - MBS8238071 from MyBioSource
|
||||||||
shRNA set against Human SHROOM3 (NM_020859.3) - SHH407288 from Creative biogene
|
||||||||
Human SHROOM3 siRNA - orb272087 from Biorbyt
|
||||||||
SHROOM3 shRNA Plasmid (Human) - CHJ1586 from Cohesion Biosciences
|
||||||||
SHROOM3 miRNA 3'UTR clone - MiUTR4H-TG08060 from Creative biogene
|