UBIAD1

Gene Symbol UBIAD1
Entrez Gene 29914
Alt Symbol SCCD, TERE1
Species Human
Gene Type protein-coding
Description UbiA prenyltransferase domain containing 1
Other Description transitional epithelia response protein|transitional epithelial response protein 1|ubiA prenyltransferase domain-containing protein 1
Swissprots B3KQG3 Q9Y5Z9 Q5THD4 Q53GX3
Accessions CAF86981 EAW71686 Q9Y5Z9 AA505091 AF117064 AAD27581 AK027433 AK074487 AK074890 BAG52025 AK222808 BAD96528 BC004468 AAH04468 BT006832 AAP35478 BX507524 XM_006710590 XP_006710653 XM_011541304 XP_011539606 XR_946616 NM_013319 NP_037451
Function Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2- methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress. {ECO:0000269|PubMed:20953171, ECO:0000269|PubMed:23374346}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion membrane. Cytoplasm. Nucleus.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11314041}.

TERE1 CRISPR/Cas9 KO Plasmid (h) - sc-402125 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 HDR Plasmid (h) - sc-402125-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 Double Nickase Plasmid (h) - sc-402125-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 Double Nickase Plasmid (h2) - sc-402125-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 CRISPR Activation Plasmid (h) - sc-402125-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 CRISPR Activation Plasmid (h2) - sc-402125-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 Lentiviral Activation Particles (h) - sc-402125-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 Lentiviral Activation Particles (h2) - sc-402125-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TERE1 siRNA (h) - sc-61667 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TERE1 shRNA Plasmid (h) - sc-61667-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TERE1 shRNA (h) Lentiviral Particles - sc-61667-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU055991 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22398 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22398 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01224 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01224

UBIAD1 siRNA (Human) - CRH9264 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBIAD1 - MBS8225552 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UBIAD1 (NM_013319.2) - SHH439324 from Creative biogene

Category siRNA
Species Reactivities Human

Human UBIAD1 siRNA - orb269766 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UBIAD1 shRNA Plasmid (Human) - CHH9264 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UBIAD1 miRNA 3'UTR clone - MiUTR4H-TG09609 from Creative biogene

Species Reactivities Human
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