Casp4

Gene Symbol Casp4
Entrez Gene 12363
Alt Symbol CASP-11, CASP-4, Casp11, Caspl, ich-3
Species Mouse
Gene Type protein-coding
Description caspase 4, apoptosis-related cysteine peptidase
Other Description caspase 11, apoptosis-related cysteine peptidase|caspase 11, apoptosis-related cysteine protease|caspase 4, apoptosis-related cysteine protease|caspase-11 short form splicing|caspase-4|protease ICH-3
Swissprots P70343 O08735 Q3TAF3
Accessions EDL09318 EDL09319 P70343 AB480706 BAH96541 AK078836 AK138730 AK151547 BAE30493 AK156667 AK160328 AK171877 BAE42715 BC061255 AAH61255 BF018212 U59463 AAB09469 Y13089 CAA73531 XM_006509837 XP_006509900 XM_006509838 XP_006509901 XM_006509839 XP_006509902 NM_007609 NP_031635
Function Involved in ER-stress induced apoptosis. Cleaves caspase-1 (By similarity). Involved in the activation cascade of caspases responsible for apoptosis execution. Promotes IL-1 beta processing by ICE, so may also have a role in inflammatory responses. {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}. Mitochondrion {ECO:0000250}.
Tissue Specificity Mostly expressed in lung and spleen; weaker in heart and lung; little in liver, skeletal muscle, kidney and testis. Not found in the brain.

Caspase-11 (17D9) Rat mAb - 14340 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rat
Clonality Monoclonal
Clone 17D9
Western blot analysis of extracts from Raw 264.7 or J774.1 cells, untreated (-) or treated with LPS (1 μg/ml, overnight; +) using Caspase-11 (17D9) Rat mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

caspase-11 (M-20) - sc-15882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

caspase-11 (17D9) - sc-56038 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

caspase-11 (F-16) - sc-15881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

caspase-11 p10 (M-50) - sc-28231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
caspase-11 p10 (M-50): sc-28231. Western blot analysis of caspase-11 precursor expression in rat skeletal muscle tissue extract.

caspase-11 p20 (M-55) - sc-28230 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
caspase-11 p20 (M-55): sc-28230. Western blot analysis of caspase-11 p20 expression in LPS/IFNγ treated RAW 264.7 (A), C6 (B) and RAW 309 (C) whole cell lysates.

caspase-11 p20 (A-2) - sc-374615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
caspase-11 p20 (A-2): sc-374615. Western blot analysis of caspase-11 p20 expression in LPS/IFNγ treated RAW 264.7 (A) and C6 (B) whole cell lysates.

Anti-Caspase-11 antibody - ab22684 from Abcam

Prices $372.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caspase-11 antibody (ab22684) at 1/10000 dilutionLane 1 : Mouse liver whole cell lysateLane 2 : Mouse hepatocyte whole cell lysateLysates/proteins at 25 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG polyclonal at 1/20000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Caspase-11 antibody - ab128850 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caspase-11 antibody (ab128850) at 1 µg/mlLane 1 : Heart (Mouse) Tissue LysateLane 2 : Skeletal Muscle (Mouse) Tissue LysateLane 3 : Brain (Mouse) Tissue LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Caspase-11 antibody [17D9] - ab10454 from Abcam

Prices $372.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) - NB120-10454 from Novus Biologicals

Prices $99.00, $339.00
Sizes 25 µl, 100 µl
Host Rat
Clonality Monoclonal
Clone 17D9
Western Blot: Caspase-11 Antibody (17D9) [NB120-10454] - Analysis of Caspase-11 in THP-1 cell lysates that were untreated (left lane) or treated (right lane) with 100 ng/ml LPS. Image from verified customer review.

Caspase-11 Antibody - NBP1-45453 from Novus Biologicals

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Caspase-11 Antibody [NBP1-45453] - Western blot analysis of Caspase 11 with 3T3 cell lysate.

Caspase-11 Antibody (17D9) [PerCP] - NB120-10454PCP from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [PE] - NB120-10454PE from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [HRP] - NB120-10454H from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 755] - NB120-10454IR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 680] - NB120-10454FR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 650] - NB120-10454C from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 550] - NB120-10454R from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 488] - NB120-10454G from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 405LS] - NB120-10454V3 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 405] - NB120-10454V from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [DyLight 350] - NB120-10454UV from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [Biotin] - NB120-10454B from Novus Biologicals

Prices $299.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9

Caspase-11 Antibody (17D9) [Allophycocyanin] - NB120-10454APC from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 17D9
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