Gene Symbol | Casp4 |
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Entrez Gene | 12363 |
Alt Symbol | CASP-11, CASP-4, Casp11, Caspl, ich-3 |
Species | Mouse |
Gene Type | protein-coding |
Description | caspase 4, apoptosis-related cysteine peptidase |
Other Description | caspase 11, apoptosis-related cysteine peptidase|caspase 11, apoptosis-related cysteine protease|caspase 4, apoptosis-related cysteine protease|caspase-11 short form splicing|caspase-4|protease ICH-3 |
Swissprots | P70343 O08735 Q3TAF3 |
Accessions | EDL09318 EDL09319 P70343 AB480706 BAH96541 AK078836 AK138730 AK151547 BAE30493 AK156667 AK160328 AK171877 BAE42715 BC061255 AAH61255 BF018212 U59463 AAB09469 Y13089 CAA73531 XM_006509837 XP_006509900 XM_006509838 XP_006509901 XM_006509839 XP_006509902 NM_007609 NP_031635 |
Function | Involved in ER-stress induced apoptosis. Cleaves caspase-1 (By similarity). Involved in the activation cascade of caspases responsible for apoptosis execution. Promotes IL-1 beta processing by ICE, so may also have a role in inflammatory responses. {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}. Mitochondrion {ECO:0000250}. |
Tissue Specificity | Mostly expressed in lung and spleen; weaker in heart and lung; little in liver, skeletal muscle, kidney and testis. Not found in the brain. |
Mouse Caspase 4 Protein - abx065764 from Abbexa
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Mouse Caspase 4 Protein - abx065765 from Abbexa
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Caspase-11 Control Peptide - AP00008CP-N from Acris Antibodies
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Caspase 4 (CASP4), Mouse - 20-7965 from ARP American Research Products
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Caspase 4 (CASP4), Mouse - 20-7966 from ARP American Research Products
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Recombinant Mouse Caspase-4(Casp4) - CSB-YP004549MO CSB-EP004549MO CSB-BP004549MO CSB-MP004549MO from Cusabio
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Caspase 4 (CASP4), Recombinant Protein - MBS2010128 from MyBioSource
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Caspase 4 (CASP4), Recombinant Protein - MBS2010519 from MyBioSource
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Caspase-4 (Casp4), Recombinant Protein - MBS956342 from MyBioSource
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Caspase-11, Peptide - MBS843761 from MyBioSource
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Recombinant Mouse CASP4 Protein - CASP4-2753M from Creative Biomart
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CASP4 Recombinant Protein (OPCD01890) - OPCD01890 from Aviva Systems Biology
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CASP4 Recombinant Protein (OPCD01895) - OPCD01895 from Aviva Systems Biology
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