Gene Symbol | M6pr |
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Entrez Gene | 312689 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | mannose-6-phosphate receptor, cation dependent |
Other Description | CD Man-6-P receptor|CD-MPR|cation-dependent mannose-6-phosphate receptor |
Swissprots | Q6AY20 |
Accessions | EDM01998 EDM01999 Q6AY20 BC079226 AAH79226 XM_008763247 XP_008761469 XM_008763248 XP_008761470 NM_001007700 NP_001007701 |
Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex (By similarity). {ECO:0000250}. |
Subcellular Location | Lysosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Top Pathways | Lysosome, Phagosome |
Recombinant Rat Cation-dependent mannose-6-phosphate receptor(M6pr) - CSB-YP731818RA CSB-EP731818RA CSB-BP731818RA CSB-MP731818RA from Cusabio
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Cation-dependent mannose-6-phosphate receptor (M6pr), Recombinant Protein - MBS1370365 from MyBioSource
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Recombinant Rat M6PR Protein - M6PR-3526R from Creative Biomart
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