GRIN1

Gene Symbol	GRIN1
Entrez Gene	2902
Alt Symbol	GluN1, MRD8, NMD-R1, NMDA1, NMDAR1, NR1
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, N-methyl D-aspartate 1
Other Description	N-methyl-D-aspartate receptor channel, subunit zeta-1|N-methyl-D-aspartate receptor subunit NR1|glutamate [NMDA] receptor subunit zeta 1|glutamate [NMDA] receptor subunit zeta-1|glutamate receptor ionotropic, NMDA 1
Swissprots	Q5VSF6 Q5VSF3 A6NLK7 Q5VSF5 Q12868 Q9UPF9 Q05586 Q12867 Q5VSF4 A6NLR1 Q5VSF8 P35437 Q9UPF8 Q5VSF7 C9K0X1
Accessions	EAW88350 EAW88351 EAW88352 EAW88353 EAW88354 EAW88355 EAW88356 EAW88357 EAW88358 EAW88359 EAW88360 Q05586 AB208918 BAD92155 AB208999 BAD92236 AF015730 AAB67723 AF015731 AAB67724 BC156097 AAI56098 BC156961 AAI56962 BU728516 D13515 BAA02732 L05666 AAA21180 L13266 AAB59360 L13267 AAA36198 L13268 AAB59361 S57708 AAB25917 U08106 AAA62111 U08107 AAA62112 XM_005266071 XP_005266128 XM_005266072 XP_005266129 XM_005266073 XP_005266130 XM_011518583 XP_011516885 NM_000832 NP_000823 NM_001185090 NP_001172019 NM_001185091 NP_001172020 NM_007327 NP_015566 NM_021569 NP_067544
Function	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. {ECO:0000250}.
Top Pathways	Amphetamine addiction, Circadian entrainment, Alcoholism, cAMP signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GRIN1 overexpression lysate - LY402129 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

GRIN1 293 Cell Lysate - 401883 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

GRIN1 293 Cell Lysate - 410125 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

NMDAR1 Overexpression Lysate (Native) - NBL1-11338 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

GRIN1 Over-expression Lysate Product - GWB-E637F8 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

GRIN1 Over-expression Lysate Product - GWB-71A32B from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

NMDAR1 Overexpression Lysate (Native) - NBP2-10710 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

NMDAR1 Overexpression Lysate (Native) - NBP2-11163 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Panoply™ Human GRIN1 Knockdown Stable Cell Line - CSC-DC006658 from Creative biogene Category Cell Line Species Human

GRIN1 Knockout Cell Line-HeLa - CSC-RT2072 from Creative biogene Category Cell Line Species Human

GRIN1 KO Cell Lysate-HeLa - CLKO-1933 from Creative biogene Category Cell Lysate

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