DNM2

Gene Symbol	DNM2
Entrez Gene	1785
Alt Symbol	CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Species	Human
Gene Type	protein-coding
Description	dynamin 2
Other Description	dynamin II|dynamin-2
Swissprots	A8K1B6 Q7Z5S3 Q9UPH4 Q5I0Y0 K7ESI9 E7EV30 P50570 E9PEQ4
Accessions	AAD23603 AAD23604 EAW84144 EAW84145 EAW84146 EAW84147 EAW84148 EAW84149 EAW84150 EAW84151 P50570 AB209213 BAD92450 AK023207 AK094984 BAG52966 AK097875 BAC05190 AK097967 AK097989 BAG53560 AK124881 BAC85978 AK126192 BAC86481 AK127033 BAC86797 AK289831 BAF82520 AK295929 BAG58715 AK312260 AY927542 BC039596 AAH39596 BC054501 AAH54501 BM148999 BU621654 DB069057 DQ594929 L36983 AAA88025 NM_001005360 NP_001005360 NM_001005361 NP_001005361 NM_001005362 NP_001005362 NM_001190716 NP_001177645 NM_004945 NP_004936
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. {ECO:0000250|UniProtKB:P39052, ECO:0000269|PubMed:12498685}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells. {ECO:0000250|UniProtKB:P39052}.
Tissue Specificity	Ubiquitously expressed.
Top Pathways	Fc gamma R-mediated phagocytosis, Endocytosis, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption, Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Dynamin 2 peptide - ab4985 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human Dynamin 2 full length protein - ab132947 from Abcam Category Protein Source Wheat germ Species Human

Human Dynamin 2 peptide - ab71849 from Abcam Category Peptide

Recombinant Human Dynamin 2 Protein - H00001785-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Dynamin 2 Protein - H00001785-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DNM2-Antibody-N-term-Blocking-Peptide - BP6843a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Dynamin-2 - H00001785-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Dynamin-2 - H00001785-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Dynamin-2 - H00001785-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Dynamin-2 - H00001785-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Dynamin-2 control peptide - SP5240CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

DNM2 fusion protein - Ag6156 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

DNM2 fusion protein - Ag6274 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DNM2, GST-tagged - DNM2-12105H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human DNM2, MYC/DDK-tagged - DNM2-17H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human DNM2, MYC/DDK-tagged - DNM2-18H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human DNM2, His-tagged - DNM2-26990TH from Creative Biomart Category Protein Source E. coli

Recombinant Dynamin 2 (DNM2) - RPB164Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Dynamin 2 (DNM2) - RPB164Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Dynamin-2(DNM2) ,partial - CSB-YP007079HU CSB-EP007079HU CSB-BP007079HU CSB-MP007079HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DNM2 Peptide - abx164839 from Abbexa Category Peptide Species Human, Mouse, Rat

Dynamin 2 Protein (Recombinant) - abx166848 from Abbexa Category Protein Source Human Species Human

Dynamin-2 (transcript variant 3) - TP308525 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Dynamin-2 (transcript variant 1) - TP323585 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Dynamin 2 Protein - NBP2-47477PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

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