DNM2

Gene Symbol	DNM2
Entrez Gene	1785
Alt Symbol	CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Species	Human
Gene Type	protein-coding
Description	dynamin 2
Other Description	dynamin II|dynamin-2
Swissprots	A8K1B6 Q7Z5S3 Q9UPH4 Q5I0Y0 K7ESI9 E7EV30 P50570 E9PEQ4
Accessions	AAD23603 AAD23604 EAW84144 EAW84145 EAW84146 EAW84147 EAW84148 EAW84149 EAW84150 EAW84151 P50570 AB209213 BAD92450 AK023207 AK094984 BAG52966 AK097875 BAC05190 AK097967 AK097989 BAG53560 AK124881 BAC85978 AK126192 BAC86481 AK127033 BAC86797 AK289831 BAF82520 AK295929 BAG58715 AK312260 AY927542 BC039596 AAH39596 BC054501 AAH54501 BM148999 BU621654 DB069057 DQ594929 L36983 AAA88025 NM_001005360 NP_001005360 NM_001005361 NP_001005361 NM_001005362 NP_001005362 NM_001190716 NP_001177645 NM_004945 NP_004936
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. {ECO:0000250|UniProtKB:P39052, ECO:0000269|PubMed:12498685}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells. {ECO:0000250|UniProtKB:P39052}.
Tissue Specificity	Ubiquitously expressed.
Top Pathways	Fc gamma R-mediated phagocytosis, Endocytosis, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption, Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Dynamin II (5E4C2F3) - sc-81150 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Dynamin II (C-18) - sc-6400 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Dynamin II (B-4) - sc-166525 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Dynamin II (G-4) - sc-166669 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Dynamin II (B-2) - sc-166526 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Anti-Dynamin 2 antibody - ab3457 from Abcam Prices $401.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Dynamin 2 antibody - ab65556 from Abcam Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Dynamin 2 antibody - ab82826 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Dynamin 2 antibody - ab55817 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Dynamin 2 antibody - ab124251 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Dynamin 2 antibody [5E4C2F3] - ab52269 from Abcam Host Mouse Clonality Monoclonal Clone 5E4C2F3

Anti-Dynamin 2 antibody [EPR9053(2)(ABC)] - ab151555 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR9053(2)(ABC)

Anti-Dynamin 2 antibody - N-terminal - ab167434 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (aa760-779) - LS-C22958 from LifeSpan Bioscience Prices $495.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (N-Terminus) - LS-C47081 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody - LS-C65077 from LifeSpan Bioscience Host Mouse Clonality Monoclonal

Anti-DNM2 / Dynamin-2 Antibody (aa611-710, clone 10C23, Azide-free) - LS-C183578 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 10C23

Anti-DNM2 / Dynamin-2 Antibody (aa625-675) - LS-C290183 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (aa750-800) - LS-C290184 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (clone 5E4C2F3) - LS-C47201 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 5E4C2F3

Anti-DNM2 / Dynamin-2 Antibody (clone 6C9) - LS-C197066 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6C9

Anti-DNM2 / Dynamin-2 Antibody (aa533-731) - LS-C314708 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (N-Terminus) - LS-C345886 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody - LS-C335096 from LifeSpan Bioscience Prices $305.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-DNM2 / Dynamin-2 Antibody (clone 5E4C2F3) - LS-C82110 from LifeSpan Bioscience Prices $445.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone 5E4C2F3

Search more