ZBTB7A

Gene Symbol ZBTB7A
Entrez Gene 51341
Alt Symbol FBI-1, FBI1, LRF, ZBTB7, ZNF857A, pokemon
Species Human
Gene Type protein-coding
Description zinc finger and BTB domain containing 7A
Other Description HIV-1 1st-binding protein 1|HIV-1 inducer of short transcripts binding protein|POK erythroid myeloid ontogenic factor|POZ and Krueppel erythroid myeloid ontogenic factor|TIP21|TTF-I-interacting peptide 21|factor binding IST protein 1|factor that binds to inducer of short transcripts protein 1|leukemia/lymphoma-related factor|lymphoma related factor|zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein|zinc finger and BTB domain-containing protein 7A|zinc finger protein 857A
Swissprots Q5XG86 O00456 O95365 Q14D41 D6W619
Accessions EAW69266 EAW69267 EAW69268 EAW69269 EAW69270 EAW69271 EAW69272 O95365 AF000561 AAB58414 AF097916 AAC72973 AL390151 BC019108 AAH19108 BC080608 BC084568 AAH84568 BC113511 AAI13512 BM696365 BQ082585 BQ711712 CB047382 CB242327 XM_005259570 XP_005259627 XM_005259571 XP_005259628 XM_005259572 XP_005259629 NM_015898 NP_056982
Function Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1- dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level). {ECO:0000269|PubMed:15662416, ECO:0000269|PubMed:9927193}.

LRF/Pokemon Antibody - 13097 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using LRF/Pokemon Antibody.

LRF (13E9) - sc-33683 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Hamster
Clonality Monoclonal
LRF (13E9): sc-33683. Western blot analysis of LRF protein showing expression in mouse embryonic fibroblasts. Kindly provided by Dr. Takahiro Maeda at Memorial Sloan-Kettering Cancer Center.

LRF (H-6) - sc-393012 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LRF (H-6): sc-393012. Western blot analysis of LRF expression in K-562 (A) and SK-MEL-28 (B) nuclear extracts.

LRF (H-180) - sc-66953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LRF (H-180): sc-66953. Immunofluorescence staining of formalin-fixed HepG2 cells showing nuclear localization.

LRF (C-18) - sc-34508 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LRF (C-18): sc-34508. Western blot analysis of LRF expression in K-562 (A) and C32 (B) nuclear extracts.

LRF (E-15) - sc-34510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LRF (E-15): sc-34510. Western blot analysis of LRF expression in Hep G2 nuclear extract.

LRF (P-14) - sc-34511 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LRF (P-14): sc-34511. Immunofluorescence staining of formalin-fixed HepG2 cells showing nuclear localization.

Anti-Pokemon antibody - ab70208 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling Pokemon with ab70208 at 1/200 (1µg/ml). Detection: DAB.

Anti-Pokemon antibody - ab52066 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Pokemon antibody - ab83197 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Pokemon antibody (ab83197) at 1 µg/ml + HeLa cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ZBTB7A antibody - ab106592 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of ZBTB7A in Human ovary tissue with ab106592 at 20 ug/mL.

Anti-ZBTB7A antibody - ab133214 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human small intestine tissue labelling ZBTB7A with ab133214 at 5ug/ml; followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-ZBTB7A antibody - ab114074 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab114074 at 1/250 dilution staining ZBTB7A in Formalin-Fixed, Paraffin-Embedded Human Breast carcinoma tissue by Immunohistochemistry. Detection utilised DAB.

Anti-ZBTB7A antibody - ab123075 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ZBTB7A antibody (ab123075) at 1/500 dilution + A549 cell line lysates at 35 µg

Anti-ZBTB7A antibody [EPR13178(B)] - ab175918 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13178(B)
All lanes : Anti-ZBTB7A antibody [EPR13178(B)] (ab175918) at 1/10000 dilutionLane 1 : MCF-7 cell lysateLane 2 : HepG2 cell lysateLane 3 : K562 cell lysateLane 4 : Hela cell lysateLysates/proteins at 10 µg per lane.

Anti-ZBTB7A antibody - N-terminal - ab182116 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ZBTB7A antibody - N-terminal (ab182116) at 1 µg/ml + Human liver tumor lysates at 10 µg

Anti-ZBTB7A / Pokemon Antibody (N-Terminus) - LS-C26360 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody - LS-C48713 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody (aa200-250) - LS-C92021 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody (aa114-163) - LS-C31254 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
NIH 3T3 Cell Lysate

Anti-ZBTB7A / Pokemon Antibody (C-Terminus) - LS-C92022 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody (aa1-50) - LS-C191214 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody (aa224-273) - LS-C31301 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-ZBTB7A / Pokemon Antibody (aa514-542, AP) - LS-C273905 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB7A / Pokemon Antibody (aa514-542, APC) - LS-C273906 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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