ADD2

Gene Symbol ADD2
Entrez Gene 119
Alt Symbol ADDB
Species Human
Gene Type protein-coding
Description adducin 2 (beta)
Other Description beta-adducin|erythrocyte adducin subunit beta
Swissprots Q7Z688 B4DM17 P35612 Q6PGQ4 D6W5G8 D6W5G7 Q6P0P2 Q13482 Q7Z691 Q7Z690 Q5U5P4 Q59G82 Q7Z689 Q16412 A8K4P2
Accessions AAD12715 AAD14349 EAW99798 EAW99799 EAW99800 EAW99801 EAW99802 EAW99803 EAW99804 EAW99805 EAW99806 EAW99807 EAW99808 P35612 AB209227 BAD92464 AB593080 BAJ84020 AF486420 AAP71863 AF486421 AAP71864 AF486422 AAP71865 AF486423 AAP71866 AK291007 BAF83696 AK297250 BAG59729 AK309773 BC008709 AAH08709 BC010237 AAH10237 BC011416 BC027876 BC041666 AAH41666 BC051882 AAH51882 BC056881 AAH56881 BC065525 AAH65525 BX119247 CN428088 DA501584 N53078 U43959 AAA86421 XM_011532502 XP_011530804 XM_011532503 XP_011530805 NM_001185054 NP_001171983 NM_001185055 NP_001171984 NM_001617 NP_001608 NM_017482 NP_059516 NM_017488 NP_059522 NM_017483 NM_017484 NM_017485 NM_017486 NM_017487
Function Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. {ECO:0000269|PubMed:18347014}.
Subcellular Location Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Tissue Specificity Expressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line. {ECO:0000269|PubMed:12951058}.

Adducin β (C-16) - sc-11880 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Adducin β (H-120) - sc-25732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Adducin β (H-120): sc-25732. Immunofluorescence staining of normal mouse spleen frozen section showing cytoplasmic staining.

Adducin β (N-19) - sc-11878 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Adducin β (N-19): sc-11878. Western blot analysis of Adducin β expression in non-transfected: sc-117752 (A) and human Adducinβ transfected: sc-117077 (B) 293T whole cell lysates.

Anti-Adducin (phospho T445) antibody - ab58485 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58485 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

Anti-Adducin 2 antibody - ab101668 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Adducin 2 antibody (ab101668) at 1/500 dilution + Human fetal brain lysate

Anti-Adducin 2 antibody - ab134976 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Adducin 2 antibody (ab134976) at 1/500 dilution + Hela cell lysate at 30 µg

Anti-Adducin antibody - ab176699 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Adducin antibody (ab176699) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Adducin antibody - ab58480 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab58480 at a dilution of 1/50. Right hand image: treated with immunising peptide. Left hand image: untreated.

Anti-ADD2 Antibody (aa471-520) - LS-C119380 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using ADD2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-ADD2 Antibody (aa550-600) - LS-C290396 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADD2 Antibody (aa600-650) - LS-C290397 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADD2 Antibody (aa448-497) - LS-C200089 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using ADD2 antibody.

Anti-ADD2 Antibody (aa648-697) - LS-C102423 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ADD2 antibody LS-C102423 Western blot of Transfected 293T cell lysate.

Anti-ADD2 Antibody (aa1-50) - LS-C290398 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADD2 Antibody - LS-C306106 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ADD2 Antibody - LS-C309329 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

beta Adducin Antibody - NBP1-53079 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: beta Adducin Antibody [NBP1-53079] - Transfected 293T tissue lysate at a concentration of 1ug/ml.

beta Adducin Antibody - NBP2-33974 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: beta Adducin Antibody [NBP2-33974] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue.  Lane 6: Human tonsil tissue

beta Adducin Antibody - NBP2-33975 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: beta Adducin Antibody [NBP2-33975] - bone marrow

beta Adducin Antibody - NBP2-15574 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: beta Adducin Antibody [NBP2-15574] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 7. 5% SDS PAGE gel, diluted at 1:500.

beta Adducin Antibody - NBP2-15573 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: beta Adducin Antibody [NBP2-15573] - Sample (30 ug of whole cell lysate) A: HUVEC 7. 5% SDS PAGE gel, diluted at 1:1000.

beta Adducin Antibody - H00000119-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: beta Adducin Antibody [H00000119-B01P] - Analysis of ADD2 expression in transfected 293T cell line by ADD2 polyclonal antibody.  Lane 1: ADD2 transfected lysate(79.86 KDa). Lane 2: Non-transfected lysate.

beta Adducin Antibody - H00000119-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: beta Adducin Antibody [H00000119-D01P] - Analysis of ADD2 expression in transfected 293T cell line by ADD2 polyclonal antibody.Lane 1: ADD2 transfected lysate(80.80 KDa).Lane 2: Non-transfected lysate.

beta Adducin Antibody - H00000119-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADD2 (456-470) antibody produced in rabbit - A7359 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ADD2 (456-470): <B>Cat. No. A7359</B>: Immunofluorescence of HUVEC cells using ADD2 (456-470), Cat. No. A7359 (red) at a 1:200 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com
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